Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDCD1 | Q15116 | 1/20 | 0.34 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.34 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.34 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.33 |
| ▸ | PRKDC | P78527 | 2/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | VCP | P55072 | 6/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | KLK8 | O60259 | 1/20 | 0.32 |
| ▸ | F2 | P00734 | 1/20 | 0.32 |
| ▸ | F10 | P00742 | 1/20 | 0.32 |
| ▸ | PLAU | P00749 | 1/20 | 0.32 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.32 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
| ▸ | KLK14 | Q9P0G3 | 1/20 | 0.32 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.32 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6957976 | 0.88 | P2RY12 (0.35) | PDCD1CD274P2RY12PDE3BPDE3A | |
| SCHEMBL8535930 | 0.79 | VCP (0.39) | VCP | |
| SCHEMBL6957968 | 0.78 | PDE4A (0.36) | PDCD1CD274P2RY12PDE3BPDE3A | |
| SCHEMBL8538658 | 0.77 | ABCB1 (0.44) | ALDH1A1KMT2A | |
| SCHEMBL6964221 | 0.73 | HTR1A (0.41) | P2RY12PDE3BPDE3APRKDCPIK3CD | |
| SCHEMBL6964162 | 0.72 | PDE3B (0.46) | P2RY12PDE3BPDE3APRKDCALDH1A1 | |
| SCHEMBL7370955 | 0.68 | TERT (0.38) | PRKDCALDH1A1VKORC1 | |
| SCHEMBL6966209 | 0.66 | FFAR4 (0.40) | ALDH1A1 | |
| SCHEMBL6955480 | 0.66 | GPR132 (0.42) | ALDH1A1KMT2A | |
| SCHEMBL8540378 | 0.66 | ACHE (0.48) | PRKDC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5808062-A | AIDS THERAPY | WARNER-LAMBERT COMPANY (US) | 1998-09-15 | — | — | US | disclosed |