Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | ABCB1 | P08183 | 4/20 | 0.41 |
| ▸ | CCNC | P24863 | 3/20 | 0.41 |
| ▸ | CDK8 | P49336 | 3/20 | 0.41 |
| ▸ | DAO | P14920 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 5/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | PTGES | O14684 | 2/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | TP53 | P04637 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 4/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.40 |
| ▸ | CYP1A1 | P04798 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6955608 | 0.94 | SMN1; SMN2 (0.50) | SMN1; SMN2L3MBTL1POLBABCB1CCNC | |
| SCHEMBL8538695 | 0.92 | POLB (0.41) | SMN1; SMN2L3MBTL1POLBABCB1CCNC | |
| SCHEMBL7374354 | 0.88 | SMN1; SMN2 (0.45) | SMN1; SMN2L3MBTL1POLBABCB1MEN1 | |
| SCHEMBL8536190 | 0.85 | SMN1; SMN2 (0.40) | SMN1; SMN2L3MBTL1POLBABCB1DAO | |
| SCHEMBL7374377 | 0.78 | ALDH1A1 (0.46) | SMN1; SMN2L3MBTL1POLBABCB1CCNC | |
| SCHEMBL8536188 | 0.78 | HDAC4 (0.41) | SMN1; SMN2L3MBTL1POLBABCB1DAO | |
| SCHEMBL6959106 | 0.77 | SMN1; SMN2 (0.47) | SMN1; SMN2L3MBTL1POLBABCB1CCNC | |
| SCHEMBL8116897 | 0.74 | SMN1; SMN2 (0.52) | SMN1; SMN2L3MBTL1POLBABCB1CCNC | |
| SCHEMBL7372932 | 0.74 | SMN1; SMN2 (0.52) | SMN1; SMN2L3MBTL1POLBABCB1CCNC | |
| SCHEMBL7366840 | 0.74 | SMN1; SMN2 (0.41) | SMN1; SMN2L3MBTL1POLBABCB1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5808062-A | AIDS THERAPY | WARNER-LAMBERT COMPANY (US) | 1998-09-15 | — | — | US | disclosed |