Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 18/20 | 0.59 |
| ▸ | ITGAV | P06756 | 18/20 | 0.59 |
| ▸ | ITGA2B | P08514 | 18/20 | 0.59 |
| ▸ | ITGB1 | P05556 | 10/20 | 0.58 |
| ▸ | ITGB5 | P18084 | 10/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8541005 | 0.83 | ITGB3 (0.50) | ITGB3ITGAVITGA2BITGB1ITGB5 | |
| SCHEMBL6225428 | 0.78 | ITGB3 (0.63) | ITGB3ITGAVITGA2BITGB1ITGB5 | |
| SCHEMBL30073956 | 0.78 | ITGB3 (0.63) | ITGB3ITGAVITGA2BITGB1ITGB5 | |
| SCHEMBL8538784 | 0.77 | ITGB3 (0.56) | ITGB3ITGAVITGA2BITGB1ITGB5 | |
| SCHEMBL7496449 | 0.74 | ITGB3 (1.00) | ITGB3ITGAVITGA2BITGB1ITGB5 | |
| SCHEMBL7496458 | 0.74 | ITGB3 (1.00) | ITGB3ITGAVITGA2BITGB1ITGB5 | |
| SCHEMBL8537894 | 0.74 | ITGB3 (0.50) | ITGB3ITGAVITGA2BITGB1ITGB5 | |
| SCHEMBL8537499 | 0.73 | ITGB3 (0.56) | ITGB3ITGAVITGA2BITGB1ITGB5 | |
| SCHEMBL8537870 | 0.73 | ITGB3 (0.49) | ITGB3ITGAVITGA2BITGB1ITGB5 | |
| SCHEMBL7379360 | 0.73 | ITGB3 (1.00) | ITGB3ITGAVITGA2BITGB1ITGB5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5852210-A | Cinnamic acid derivatives | G. D. SEARLE & CO. (US) | 1998-12-22 | — | — | US | claimed |
| US-5852210-A | Cinnamic acid derivatives | G. D. SEARLE & CO. (US) | 1998-12-22 | — | — | US | disclosed |