Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | ACP3 | P15309 | 1/20 | 0.47 |
| ▸ | SRC | P12931 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.40 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.39 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.39 |
| ▸ | CACNB1 | Q02641 | 2/20 | 0.39 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.39 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.39 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9492209 | 0.89 | SRC (0.58) | MEN1KMT2AACP3SRCPPARG | |
| SCHEMBL27780341 | 0.84 | MEN1 (0.50) | MEN1KMT2AACP3SRCNPC1 | |
| SCHEMBL349034 | 0.84 | MEN1 (0.50) | MEN1KMT2AACP3SRCPARP1 | |
| SCHEMBL17290331 | 0.82 | MEN1 (0.49) | MEN1KMT2AACP3SRCKEAP1 | |
| SCHEMBL8538429 | 0.79 | ACP3 (0.47) | ACP3SRCPARP1LMNAMAPT | |
| SCHEMBL27278586 | 0.78 | SRC (0.73) | KMT2ASRCALDH1A1LMNA | |
| SCHEMBL11000344 | 0.77 | MEN1 (0.54) | MEN1KMT2AACP3PPARGPPARA | |
| SCHEMBL15774550 | 0.77 | PARP1 (0.53) | MEN1KMT2AACP3ALDH1A1PARP1 | |
| SCHEMBL11628563 | 0.77 | ACP3 (0.49) | MEN1KMT2AACP3NPC1ALDH1A1 | |
| SCHEMBL11458526 | 0.76 | MEN1 (0.47) | MEN1KMT2AACP3SRCPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5808062-A | AIDS THERAPY | WARNER-LAMBERT COMPANY (US) | 1998-09-15 | — | — | US | disclosed |