Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | TRPM8 | Q7Z2W7 | 6/20 | 0.49 |
| ▸ | ACP3 | P15309 | 1/20 | 0.49 |
| ▸ | PARP1 | P09874 | 1/20 | 0.48 |
| ▸ | SRC | P12931 | 1/20 | 0.47 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9492209 | 0.90 | SRC (0.58) | MEN1KMT2ATRPM8ACP3PARP1 | |
| SCHEMBL15774550 | 0.90 | PARP1 (0.53) | MEN1KMT2ATRPM8ACP3PARP1 | |
| SCHEMBL27780341 | 0.85 | MEN1 (0.50) | MEN1KMT2ATRPM8ACP3PARP1 | |
| SCHEMBL17290331 | 0.84 | MEN1 (0.49) | MEN1KMT2ATRPM8ACP3PARP1 | |
| SCHEMBL8538808 | 0.84 | MEN1 (0.49) | MEN1KMT2ATRPM8ACP3PARP1 | |
| SCHEMBL3623486 | 0.79 | MEN1 (0.51) | MEN1KMT2AACP3PARP1 | |
| SCHEMBL27865867 | 0.79 | MEN1 (0.51) | MEN1KMT2AACP3PARP1 | |
| SCHEMBL29454480 | 0.79 | MEN1 (0.51) | MEN1KMT2AACP3PARP1 | |
| SCHEMBL29779063 | 0.79 | MEN1 (0.51) | MEN1KMT2AACP3PARP1 | |
| SCHEMBL29136047 | 0.79 | MEN1 (0.51) | MEN1KMT2AACP3PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120015976-A1 | AUTOTAXIN INHIBITORS | MERCK PATENT GESELLSCHAFT MIT BESCHRANK TER HAFTUNG (DE) | 2012-01-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120015976-A1 | AUTOTAXIN INHIBITORS | ENPP2, PLA2G12A, LPCAT1 | MEN1 186/4885KMT2A 1523/4885TRPM8 2579/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.