Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 3/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.40 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.40 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | PPARD | Q03181 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Anisole SCHEMBL8537548 | 0.93 | TBXAS1 (0.44) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| Trifluoromethylbenzene SCHEMBL8545298 | 0.90 | HDAC3 (0.39) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| Toluene SCHEMBL8543856 | 0.84 | TBXAS1 (0.46) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL8581509 | 0.76 | TBXAS1 (0.61) | TBXAS1 | |
| SCHEMBL8543940 | 0.75 | TBXAS1 (0.65) | TBXAS1MEN1KMT2A | |
| SCHEMBL8538149 | 0.74 | HDAC4 (0.44) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL8539906 | 0.72 | TBXAS1 (0.65) | TBXAS1 | |
| SCHEMBL8539406 | 0.71 | TBXAS1 (0.70) | TBXAS1 | |
| SCHEMBL8539323 | 0.69 | TBXAS1 (0.61) | TBXAS1 | |
| SCHEMBL8637450 | 0.68 | TBXAS1 (0.59) | TBXAS1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0715627-B1 | INDOLE DERIVATIVES AS THROMBOXANE A2 ANTAGONISTS | PFIZER LTD (GB) | 1998-09-09 | — | — | EP | claimed |