Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | TP53 | P04637 | 3/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | CCR1 | P32246 | 2/20 | 0.50 |
| ▸ | CCR5 | P51681 | 2/20 | 0.50 |
| ▸ | CCR8 | P51685 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | ALPL | P05186 | 1/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.50 |
| ▸ | ALPI | P09923 | 1/20 | 0.50 |
| ▸ | ALPG | P10696 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8538282 | 0.92 | KDM4E (0.53) | KDM4ELMNATP53ALOX15L3MBTL1 | |
| SCHEMBL30400838 | 0.89 | KDM4E (0.63) | KDM4ELMNATP53ALOX15L3MBTL1 | |
| SCHEMBL20400251 | 0.89 | KDM4E (0.63) | KDM4ELMNATP53ALOX15L3MBTL1 | |
| SCHEMBL3165466 | 0.89 | KDM4E (0.63) | KDM4ELMNATP53ALOX15L3MBTL1 | |
| SCHEMBL776048 | 0.78 | KDM4E (0.67) | KDM4ELMNATP53ALOX15L3MBTL1 | |
| SCHEMBL8539424 | 0.78 | FFAR1 (0.42) | KDM4ETDP1MAPK1GRM5 | |
| SCHEMBL30132148 | 0.76 | ALDH1A1 (0.50) | KDM4ELMNAL3MBTL1TDP1CCR1 | |
| SCHEMBL12824407 | 0.76 | KDM4E (0.71) | KDM4ELMNATP53ALOX15L3MBTL1 | |
| SCHEMBL29476108 | 0.76 | CCR1 (0.48) | KDM4ELMNATP53ALOX15L3MBTL1 | |
| SCHEMBL2151538 | 0.76 | CCR1 (0.48) | KDM4ELMNATP53ALOX15L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0588146-B1 | Substituted pyridin derivatives and parasiticides containing them | BASF AG (DE) | 1998-11-11 | — | — | EP | disclosed |
| EP-0588146-A2 | Substituted pyridin derivatives and parasiticides containing them | BASF Aktiengesellschaft (DE) | 1994-03-23 | — | — | EP | disclosed |