Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8546591 | 0.90 | — | — | |
| SCHEMBL9845667 | 0.88 | AGTR1 (0.58) | AGTR1AGTR2 | |
| SCHEMBL9845754 | 0.88 | AGTR1 (0.58) | AGTR1AGTR2 | |
| SCHEMBL9160007 | 0.86 | — | — | |
| SCHEMBL9160015 | 0.86 | — | — | |
| SCHEMBL9379473 | 0.85 | — | — | |
| SCHEMBL9432651 | 0.85 | — | — | |
| SCHEMBL9402007 | 0.85 | — | — | |
| SCHEMBL9402071 | 0.84 | PDE4A (0.64) | — | |
| Cl-329167 SCHEMBL4111462 | 0.84 | AGTR1 (0.76) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0497150-B1 | Angiotensin II receptor blocking 2,3,6-substituted quinazolones | AMERICAN CYANAMID CO (US) | 1998-03-18 | — | — | EP | claimed |
| EP-0497150-A1 | Angiotensin II receptor blocking 2,3,6-substituted quinazolones | AMERICAN CYANAMID COMPANY (US) | 1992-08-05 | — | — | EP | claimed |
| US-5405849-A | Treating hypertension, congestive heart failure | AMERICAN CYANAMID COMPANY (US) | 1995-04-11 | — | — | US | disclosed |
| US-5290780-A | Hypotensive agents; congestive heart failure | AMERICAN CYANAMID CO. (US) | 1994-03-01 | — | — | US | disclosed |