SCHEMBL8539341

SCHEMBL8539341

CCCCc1cc(C(C)(C)C)c(Oc2ccc(N)cc2)cc1C

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.39
ALDH1A1 P00352 5/20 0.39
NPC1 O15118 2/20 0.39
RAB9A P51151 2/20 0.39
HPGD P15428 1/20 0.39
MAPK1 P28482 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.36
TEAD4 Q15561 1/20 0.35
NR1H4 Q96RI1 1/20 0.34
TDP1 Q9NUW8 3/20 0.34
POLB P06746 1/20 0.34
HTR2A P28223 1/20 0.34
SKP2 Q13309 1/20 0.33
PKM P14618 1/20 0.33
TSHR P16473 2/20 0.33
CYP3A4 P08684 1/20 0.33
THRB P10828 1/20 0.32
GAA P10253 1/20 0.32
XBP1 P17861 1/20 0.32
ATM Q13315 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8535796 0.96 MAPT (0.38) MAPTALDH1A1NPC1RAB9AHPGD
SCHEMBL8536546 0.95 ALDH1A1 (0.37) MAPTALDH1A1NPC1RAB9AHPGD
SCHEMBL8537916 0.95 ALDH1A1 (0.37) MAPTALDH1A1NPC1RAB9AHPGD
SCHEMBL8565147 0.90 MAPT (0.32) MAPTALDH1A1NPC1RAB9AHPGD
SCHEMBL8561275 0.83 NPC1 (0.33) MAPTALDH1A1NPC1RAB9AHPGD
SCHEMBL8990309 0.79 TP53 (0.44) MAPTALDH1A1NPC1RAB9AHPGD
SCHEMBL8990487 0.78 TP53 (0.43) MAPTALDH1A1NPC1RAB9AHPGD
SCHEMBL8990354 0.77 TP53 (0.42) MAPTALDH1A1NPC1RAB9AHPGD
SCHEMBL1353357 0.77 ALDH1A1 (0.57) MAPTALDH1A1NPC1RAB9AHPGD
SCHEMBL5150318 0.76 TP53 (0.52) MAPTALDH1A1NPC1RAB9AHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5734008-A AROMATIC ETHERDIAMINES FOR POLYIMIDE FILMS FOR PRINTED CIRCUITS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1998-03-31 US disclosed