Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | HPGD | P15428 | 6/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | GUSB | P08236 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | MAOB | P27338 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CRHBP | P24387 | 1/20 | 0.35 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8539615 | 1.00 | ATM (0.52) | ATMSMN1; SMN2ALDH1A1HPGDCYP1A2 | |
| SCHEMBL1548278 | 0.86 | ALDH1A1 (0.54) | ATMSMN1; SMN2ALDH1A1HPGDKMT2A | |
| SCHEMBL28803834 | 0.83 | ATM (0.46) | ATMSMN1; SMN2ALDH1A1HPGDKMT2A | |
| SCHEMBL13885660 | 0.82 | ALDH1A1 (0.51) | ATMSMN1; SMN2ALDH1A1HPGDCYP1A2 | |
| SCHEMBL27907032 | 0.82 | ALDH1A1 (0.51) | ATMSMN1; SMN2ALDH1A1HPGDKMT2A | |
| SCHEMBL34460861 | 0.80 | TSHR (0.50) | ATMSMN1; SMN2ALDH1A1HPGDKMT2A | |
| SCHEMBL31158568 | 0.80 | TSHR (0.50) | ATMSMN1; SMN2ALDH1A1HPGDKMT2A | |
| SCHEMBL9790616 | 0.80 | ATM (0.43) | ATMSMN1; SMN2ALDH1A1HPGDCYP1A2 | |
| SCHEMBL27907027 | 0.78 | ALDH1A1 (0.56) | SMN1; SMN2ALDH1A1HPGDMAPTMAOB | |
| SCHEMBL31470938 | 0.75 | MAOB (0.45) | ATMSMN1; SMN2ALDH1A1HPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0683156-B1 | Acylated aminoalkanimidazoles and -triazoles | CIBA GEIGY AG (CH) | 1998-04-01 | — | — | EP | disclosed |
| US-5622982-A | ENZYME INHIBITORS; ANTIINFLAMMATORY AGENTS | SANDOZ LTD. (CH) | 1997-04-22 | — | — | US | disclosed |
| EP-0683156-A1 | Acylated aminoalkanimidazoles and -triazoles | SANDOZ LTD. (CH) | 1995-11-22 | — | — | EP | disclosed |