Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | BRAF | P15056 | 4/20 | 0.45 |
| ▸ | RAF1 | P04049 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Isoxaben SCHEMBL54432 | 1.00 | CYP1A2 (0.53) | CYP1A2CYP3A4CYP2C19BRAFRAF1 | |
| Isoxaben SCHEMBL9713018 | 0.99 | CYP1A2 (0.52) | CYP1A2CYP3A4CYP2C19BRAFRAF1 | |
| SCHEMBL16589802 | 0.93 | TAS1R3 (0.51) | CYP1A2CYP3A4CYP2C19BRAFRAF1 | |
| SCHEMBL11102585 | 0.93 | CYP1A2 (0.49) | CYP1A2CYP3A4CYP2C19BRAFRAF1 | |
| SCHEMBL9713569 | 0.93 | CYP1A2 (0.46) | CYP1A2CYP3A4CYP2C19BRAFRAF1 | |
| SCHEMBL9713162 | 0.93 | CYP1A2 (0.49) | CYP1A2CYP3A4CYP2C19BRAFRAF1 | |
| Isoxaben SCHEMBL28180388 | 0.93 | CYP1A2 (0.47) | CYP1A2CYP3A4CYP2C19BRAFRAF1 | |
| SCHEMBL9712899 | 0.92 | MAPK14 (0.50) | CYP1A2CYP3A4CYP2C19BRAFRAF1 | |
| SCHEMBL9712835 | 0.92 | CYP1A2 (0.47) | CYP1A2CYP3A4CYP2C19BRAFRAF1 | |
| SCHEMBL9712960 | 0.91 | MAPK14 (0.54) | CYP1A2CYP3A4CYP2C19BRAFRAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0574418-B1 | ARYL SULPHONYL UREA COMPOUNDS, A METHOD OF PREPARING THEM, AND THEIR USE AS HERBICIDES AND GROWTH REGULATORS | HOECHST SCHERING AGREVO GMBH (DE) | 1998-11-11 | — | — | EP | disclosed |
| US-5463081-A | Chemical intermediates | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-10-31 | — | — | US | disclosed |
| EP-0546082-A1 | HERBICIDAL PYRROLESULFONYLUREAS. | DU PONT (US) | 1993-06-16 | — | — | EP | disclosed |
| WO-1992020684-A1 | HERBICIDAL OXATRICYCLIC ETHERS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-11-26 | — | — | WO | disclosed |
| WO-1992004827-A1 | HERBICIDAL SUBSTITUTED BICYCLIC TRIAZOLES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-04-02 | — | — | WO | disclosed |