Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 1/20 | 0.53 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.53 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | BCL2 | P10415 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.46 |
| ▸ | CTSS | P25774 | 6/20 | 0.46 |
| ▸ | CTSK | P43235 | 5/20 | 0.46 |
| ▸ | YAP1 | P46937 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | CTSL | P07711 | 1/20 | 0.45 |
| ▸ | CTSB | P07858 | 1/20 | 0.45 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2523784 | 1.00 | ITGB3 (0.53) | ITGB3ITGA2BKLK5HDAC8MEN1 | |
| SCHEMBL10054710 | 0.96 | HDAC8 (0.51) | ITGB3ITGA2BKLK5HDAC8MEN1 | |
| SCHEMBL15674211 | 0.94 | ITGB3 (0.54) | ITGB3ITGA2BKLK5HDAC8MEN1 | |
| SCHEMBL15674214 | 0.94 | ITGB3 (0.54) | ITGB3ITGA2BKLK5HDAC8MEN1 | |
| SCHEMBL18025355 | 0.92 | ITGB3 (0.53) | ITGB3ITGA2BKLK5HDAC8BCL2 | |
| SCHEMBL15699462 | 0.91 | SMN1; SMN2 (0.53) | ITGB3ITGA2BHDAC8ALDH1A1BCL2 | |
| SCHEMBL2219572 | 0.90 | ITGB3 (0.66) | ITGB3ITGA2BHDAC8BCL2PTPN1 | |
| SCHEMBL15697431 | 0.90 | ITGB3 (0.54) | ITGB3ITGA2BHDAC8BCL2PTPN1 | |
| SCHEMBL7086188 | 0.90 | ITGB3 (0.66) | ITGB3ITGA2BHDAC8BCL2PTPN1 | |
| SCHEMBL2219578 | 0.90 | ITGB3 (0.66) | ITGB3ITGA2BHDAC8BCL2PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111302975-A | Preparation method of N-tert-butyloxycarbonyl-O-allyl-L-tyrosine | 滨海吉尔多肽有限公司 | 2020-06-19 | — | — | CN | disclosed |
| US-8524657-B2 | Peptidic compounds | UNIVERSITY OF WOLLONGONG (AU) | 2013-09-03 | — | — | US | disclosed |
| US-8309055-B2 | PET radiotracers | HAMMERSMITH IMANET LIMITED (GB) | 2012-11-13 | — | — | US | disclosed |
| US-20120130122-A1 | PET RADIOTRACERS | HAMMERSMITH IMANET LIMITED (GB) | 2012-05-24 | — | — | US | disclosed |
| US-20110312875-A1 | PEPTIDIC COMPOUNDS | UNIVERSITY OF WOLLONGONG (AU) | 2011-12-22 | — | — | US | disclosed |
| US-8039430-B2 | Peptidic compounds | UNIVERSITY OF WOLLONGONG (AU) | 2011-10-18 | — | — | US | disclosed |
| US-8039430-B2 | Peptidic compounds | UNIVERSITY OF WOLLONGONG (AU) | 2011-10-18 | — | — | US | disclosed |
| US-20080300287-A1 | Peptidic Compounds | UNIVERSITY OF WOLLONGONG (AU) | 2008-12-04 | — | — | US | disclosed |
| US-20080300287-A1 | Peptidic Compounds | UNIVERSITY OF WOLLONGONG (AU) | 2008-12-04 | — | — | US | disclosed |
| US-20080292552-A1 | Pet Radiotracers | ARSTAD ERIK | 2008-11-27 | — | — | US | disclosed |
| US-5599926-A | PEPTIDE BONDING PROPERTIES MAKE IT USEFUL IN PURIFICATION PROCESSES | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 1997-02-04 | — | — | US | disclosed |
| WO-1995020590-A1 | ENANTIOSELECTIVE RECEPTORS FOR AMINO ACID DERIVATIVES, AND OTHER COMPOUNDS | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 1995-08-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080300287-A1 | Peptidic Compounds | VIP, NGLY1, FURIN | ITGB3 2966/4885ITGA2B 4105/4885KLK5 85/4885 |
| US-20120130122-A1 | PET RADIOTRACERS | TMEM14C, PIGO, SLCO2B1 | ITGB3 1125/4885ITGA2B 2565/4885KLK5 1573/4885 |
| US-20110312875-A1 | PEPTIDIC COMPOUNDS | VIP, NGLY1, FURIN | ITGB3 2456/4885ITGA2B 3961/4885KLK5 80/4885 |
| US-20080292552-A1 | Pet Radiotracers | TMEM14C, PIGO, SLCO2B1 | ITGB3 1125/4885ITGA2B 2565/4885KLK5 1573/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.