Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | CASP6 | P55212 | 3/20 | 0.43 |
| ▸ | CASP3 | P42574 | 2/20 | 0.43 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.43 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | P2RX3 | P56373 | 3/20 | 0.39 |
| ▸ | P2RX2 | Q9UBL9 | 3/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | TNKS | O95271 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16456324 | 0.72 | HPGD (0.74) | HPGDKMT2ACASP6CASP3SENP8 | |
| SCHEMBL501398 | 0.72 | KMT2A (0.45) | HPGDKMT2AGAAMEN1RECQL | |
| SCHEMBL28136099 | 0.71 | HPGD (0.50) | HPGDKMT2ACASP6CASP3SENP8 | |
| SCHEMBL2340654 | 0.71 | HPGD (0.57) | HPGDKMT2ACASP6CASP3SENP8 | |
| SCHEMBL27662070 | 0.71 | HPGD (0.53) | HPGDKMT2ATDP1GAAMEN1 | |
| SCHEMBL8544919 | 0.70 | GAA (0.49) | HPGDKMT2ACASP6CASP3SENP8 | |
| SCHEMBL28133140 | 0.70 | HPGD (0.46) | HPGDKMT2ACASP6CASP3SENP8 | |
| SCHEMBL23315011 | 0.70 | SMN1; SMN2 (0.42) | HPGDKMT2ACASP6CASP3SENP8 | |
| SCHEMBL24860893 | 0.70 | HPGD (0.46) | HPGDKMT2ACASP6CASP3SENP8 | |
| SCHEMBL31593908 | 0.69 | HPGD (0.54) | HPGDKMT2ACASP6CASP3SENP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0580502-B1 | 3-(Hydroxybenzylidenyl)-indoline-2-ones and pharmaceutical compositions containing them | ADIR (FR) | 1998-09-02 | — | — | EP | disclosed |
| US-5382593-A | Antioxidants or anticoagulants | ADIR ET COMPAGNIE (FR) | 1995-01-17 | — | — | US | disclosed |
| EP-0580502-A1 | 3-(Hydroxybenzylidenyl)-indoline-2-ones and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1994-01-26 | — | — | EP | disclosed |