Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.67 |
| ▸ | GAA | P10253 | 4/20 | 0.67 |
| ▸ | MEN1 | O00255 | 4/20 | 0.67 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.67 |
| ▸ | TNKS | O95271 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | CASP6 | P55212 | 2/20 | 0.50 |
| ▸ | CASP3 | P42574 | 1/20 | 0.50 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.50 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.50 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 2/20 | 0.47 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.47 |
| ▸ | F2 | P00734 | 1/20 | 0.47 |
| ▸ | ELANE | P08246 | 1/20 | 0.47 |
| ▸ | CTSG | P08311 | 1/20 | 0.47 |
| ▸ | CMA1 | P23946 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31422646 | 0.85 | HPGD (1.00) | HPGDKMT2AGAAMEN1TLR9 | |
| SCHEMBL30681119 | 0.85 | HPGD (0.52) | HPGDKMT2AGAAMEN1TLR9 | |
| SCHEMBL143970 | 0.85 | HPGD (1.00) | HPGDKMT2AGAAMEN1TLR9 | |
| SCHEMBL10071645 | 0.85 | HPGD (0.52) | HPGDKMT2AGAAMEN1TLR9 | |
| SCHEMBL5215688 | 0.85 | HPGD (0.53) | HPGDKMT2AGAAMEN1TLR9 | |
| SCHEMBL6765903 | 0.83 | HPGD (0.74) | HPGDKMT2AGAAMEN1TLR9 | |
| SCHEMBL6328308 | 0.83 | HPGD (0.74) | HPGDKMT2AGAAMEN1TLR9 | |
| SCHEMBL6327688 | 0.83 | HPGD (0.74) | HPGDKMT2AGAAMEN1TLR9 | |
| SCHEMBL4463146 | 0.83 | HPGD (0.74) | HPGDKMT2AGAAMEN1TLR9 | |
| SCHEMBL27296976 | 0.83 | HPGD (0.74) | HPGDKMT2AGAAMEN1TLR9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9340549-B2 | Oxazolidinone compounds and derivatives thereof | AMGEN INC. (US) | 2016-05-17 | — | — | US | disclosed |
| US-20150045368-A1 | OXAZOLIDINONE COMPOUNDS AND DERIVATIVES THEREOF | AMGEN INC. | 2015-02-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150045368-A1 | OXAZOLIDINONE COMPOUNDS AND DERIVATIVES THEREOF | TNKS1BP1, TNKS, TBKBP1 | HPGD 1330/4885KMT2A 2435/4885GAA 264/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.