Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OGA | O60502 | 3/20 | 0.38 |
| ▸ | ASGR1 | P07306 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | TREH | O43280 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
| ▸ | CD69 | Q07108 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1428571 | 0.70 | TREH (0.33) | TREH | |
| SCHEMBL900085 | 0.70 | TREH (0.33) | TREH | |
| SCHEMBL27530918 | 0.70 | TREH (0.33) | TREH | |
| SCHEMBL5664627 | 0.70 | TREH (0.33) | TREH | |
| SCHEMBL23603516 | 0.69 | OGA (0.46) | OGAALDH1A1THRBMAPK1TREH | |
| SCHEMBL10557474 | 0.69 | OGA (0.46) | OGAALDH1A1THRBMAPK1TREH | |
| SCHEMBL13389865 | 0.69 | OGA (0.46) | OGAALDH1A1THRBMAPK1TREH | |
| SCHEMBL16221822 | 0.69 | OGA (0.46) | OGAALDH1A1THRBMAPK1TREH | |
| SCHEMBL12085189 | 0.69 | OGA (0.46) | OGAALDH1A1THRBMAPK1TREH | |
| SCHEMBL16869797 | 0.69 | OGA (0.46) | OGAALDH1A1THRBMAPK1TREH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0705059-A4 | CHOLESTEROL SEQUESTRANT GLYCOSIDES THAT INHIBIT INTESTINAL CHOLESTEROL ABSORPTION | OREGON MEDICAL RES FOUND (US) | 1998-07-01 | — | — | EP | claimed |
| EP-0705059-A1 | CHOLESTEROL SEQUESTRANT GLYCOSIDES THAT INHIBIT INTESTINAL CHOLESTEROL ABSORPTION | Oregon Regional Primate Research Center (US) | 1996-04-10 | — | — | EP | claimed |
| EP-0705059-A4 | CHOLESTEROL SEQUESTRANT GLYCOSIDES THAT INHIBIT INTESTINAL CHOLESTEROL ABSORPTION | OREGON MEDICAL RES FOUND (US) | 1998-07-01 | — | — | EP | disclosed |
| EP-0705059-A1 | CHOLESTEROL SEQUESTRANT GLYCOSIDES THAT INHIBIT INTESTINAL CHOLESTEROL ABSORPTION | Oregon Regional Primate Research Center (US) | 1996-04-10 | — | — | EP | disclosed |