Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 4/20 | 0.62 |
| ▸ | GRIA2 | P42262 | 4/20 | 0.62 |
| ▸ | GRIA3 | P42263 | 4/20 | 0.62 |
| ▸ | GRIA4 | P48058 | 4/20 | 0.62 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | MPO | P05164 | 3/20 | 0.47 |
| ▸ | PARP1 | P09874 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.44 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.44 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.44 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.44 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.44 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4704936 | 0.86 | GRIA1 (0.63) | GRIA1GRIA2GRIA3GRIA4PARP1 | |
| SCHEMBL31653996 | 0.86 | GRIA1 (0.63) | GRIA1GRIA2GRIA3GRIA4PARP1 | |
| SCHEMBL9396483 | 0.81 | KDM4E (0.72) | GRIA1GRIA2GRIA3GRIA4HPGD | |
| SCHEMBL24335550 | 0.78 | GRIA1 (0.57) | GRIA1GRIA2GRIA3GRIA4HPGD | |
| SCHEMBL29580203 | 0.78 | GRIA1 (0.57) | GRIA1GRIA2GRIA3GRIA4HPGD | |
| SCHEMBL9395583 | 0.77 | GRIA1 (0.54) | GRIA1GRIA2GRIA3GRIA4HPGD | |
| SCHEMBL5551602 | 0.77 | KDM4E (0.52) | GRIA1GRIA2GRIA3GRIA4MPO | |
| SCHEMBL982104 | 0.77 | CYP1A2 (0.69) | GRIA1GRIA2GRIA3GRIA4PARP1 | |
| SCHEMBL29579885 | 0.77 | CYP1A2 (0.69) | GRIA1GRIA2GRIA3GRIA4PARP1 | |
| SCHEMBL24335150 | 0.75 | ALDH1A1 (0.56) | GRIA1GRIA2GRIA3GRIA4HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0315959-B1 | Quinoxaline compounds and their preparation and use | NOVO NORDISK AS (DK) | 1994-03-02 | — | — | EP | claimed |
| EP-0873321-A1 | NOVEL AMIDO QUINOXALINE DIONES, THEIR PRODUCTION AND USE | BASF AKTIENGESELLSCHAFT (DE) | 1998-10-28 | — | — | EP | disclosed |
| US-5773439-A | Amido-quinoxalinediones, the preparation and use thereof | BASF AKTIENGESELLSCHAFT (DE) | 1998-06-30 | — | — | US | disclosed |
| WO-1995035289-A1 | NOVEL AMIDO QUINOXALINE DIONES, THEIR PRODUCTION AND USE | BASF AKTIENGESELLSCHAFT (DE) | 1995-12-28 | — | — | WO | disclosed |
| EP-0315959-B1 | Quinoxaline compounds and their preparation and use | NOVO NORDISK AS (DK) | 1994-03-02 | — | — | EP | disclosed |
| US-5026704-A | Neuroleptic agent, quisqualate-antagonist | NOVO NORDISK A/S (DK) | 1991-06-25 | — | — | US | disclosed |
| US-4948794-A | NEUROLEPTIC AGENTS | A/S FERROSAN (DK) | 1990-08-14 | — | — | US | disclosed |
| EP-0315959-A2 | Quinoxaline compounds and their preparation and use | NOVO NORDISK A/S (DK) | 1989-05-17 | — | — | EP | disclosed |