Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CETP | P11597 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8975436 | 0.83 | CETP (0.37) | CETP | |
| SCHEMBL20099457 | 0.74 | TRPV1 (0.34) | — | |
| SCHEMBL8059001 | 0.73 | SPHK1 (0.32) | CETP | |
| SCHEMBL10163389 | 0.71 | TSHR (0.31) | — | |
| SCHEMBL9216238 | 0.70 | GSR (0.40) | — | |
| SCHEMBL12321638 | 0.69 | — | — | |
| SCHEMBL771021 | 0.68 | NFKB1 (0.43) | — | |
| SCHEMBL16297104 | 0.66 | — | — | |
| SCHEMBL27470695 | 0.66 | — | — | |
| SCHEMBL7199328 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0504064-B1 | Novel thrombin inhibitors | MERRELL PHARMA INC (US) | 1998-05-13 | — | — | EP | disclosed |
| US-5563156-A | ANTICOAGULANTS, ANTIASTHMA AGENTS | MERRELL PHARMACEUTICALS INC. (US) | 1996-10-08 | — | — | US | disclosed |
| US-5498779-A | ANTICOAGULANTS AND TREATMENT OF ASTHMA | MERRELL PHARMACEUTICALS INC. (US) | 1996-03-12 | — | — | US | disclosed |
| US-5391705-A | Anticoagulants, treats thrombophlebitis, coronary thrombosis and asthma | MERRELL DOW PHARMACEUTICALS INC. (US) | 1995-02-21 | — | — | US | disclosed |
| EP-0504064-A1 | Novel thrombin inhibitors | MERRELL PHARMACEUTICALS INC. (US) | 1992-09-16 | — | — | EP | disclosed |