Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSEN1 | P49768 | 12/20 | 0.54 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | TTPA | P49638 | 2/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PDE4A | P27815 | 1/20 | 0.38 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9257213 | 0.89 | PSEN1 (0.67) | PSEN1PTGS1PTGS2CYP1A2CYP3A4 | |
| SCHEMBL15854990 | 0.88 | PSEN1 (0.54) | PSEN1PTGS1PTGS2CYP1A2CYP3A4 | |
| SCHEMBL8542595 | 0.88 | PSEN1 (0.48) | PSEN1PTGS1PTGS2CYP1A2CYP3A4 | |
| SCHEMBL9695593 | 0.85 | PTGS1 (0.52) | PSEN1PTGS1PTGS2CYP1A2CYP3A4 | |
| SCHEMBL16215097 | 0.84 | PTGS1 (0.54) | PSEN1PTGS1PTGS2CYP1A2CYP3A4 | |
| SCHEMBL8544235 | 0.81 | TTPA (0.58) | PSEN1PTGS1PTGS2CYP1A2CYP3A4 | |
| SCHEMBL9314887 | 0.79 | PSEN1 (0.51) | PSEN1PTGS1PTGS2CYP1A2CYP3A4 | |
| SCHEMBL9075342 | 0.79 | PSEN1 (0.46) | PSEN1TTPAALOX5MEN1KMT2A | |
| SCHEMBL9632542 | 0.78 | PSEN1 (0.45) | PSEN1TTPAALOX5MEN1KMT2A | |
| SCHEMBL14950826 | 0.77 | PTPN1 (0.57) | PSEN1PTGS1PTGS2CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0587499-B1 | Benzopyran compounds, process for their preparation and their use as cell protectors | ADIR (FR) | 1998-04-29 | — | — | EP | disclosed |
| EP-0587499-A1 | Benzopyran compounds, process for their preparation and their use as cell protectors | ADIR ET COMPAGNIE (FR) | 1994-03-16 | — | — | EP | disclosed |