SCHEMBL8539853

SCHEMBL8539853

COCC#Cc1ccccc1NS(=O)(=O)NC(=O)Nc1nc(C)nc(OC)n1

nearest known ligand 0.52

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.36
TP53 P04637 2/20 0.33
KDM4E B2RXH2 1/20 0.33
NPC1 O15118 1/20 0.33
ALDH1A1 P00352 1/20 0.33
SLC16A3 O15427 4/20 0.33
MAPT P10636 1/20 0.32
GAA P10253 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8540134 0.92 TP53 (0.35) ALOX15TP53KDM4ENPC1ALDH1A1
SCHEMBL8534921 0.88 ALOX15 (0.40) ALOX15TP53KDM4ENPC1ALDH1A1
SCHEMBL8536574 0.88 ALOX15 (0.38) ALOX15TP53KDM4ENPC1ALDH1A1
SCHEMBL8538403 0.87 ALOX15 (0.37) ALOX15TP53KDM4ENPC1ALDH1A1
SCHEMBL8539805 0.87 ALOX15 (0.37) ALOX15TP53KDM4ENPC1ALDH1A1
SCHEMBL8535329 0.87 GAA (0.45) ALOX15TP53SLC16A3MAPTGAA
SCHEMBL8536335 0.85 ALOX15 (0.39) ALOX15TP53KDM4ENPC1ALDH1A1
SCHEMBL8535082 0.85 ALOX15 (0.36) ALOX15TP53ALDH1A1SLC16A3MAPT
SCHEMBL8539797 0.84 ALOX15 (0.35) ALOX15TP53SLC16A3GAA
SCHEMBL8540370 0.84 ALOX15 (0.35) ALOX15TP53SLC16A3MAPTGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0770603-B1 Alkynylphenylaminosulfonyl ureas as herbicides ISAGRO RICERCA SRL (IT) 1998-09-16 EP disclosed
US-5721192-A HERBICIDES ISAGRO RICERCA S.R.L. (IT) 1998-02-24 US disclosed
EP-0770603-A1 Alkynylphenylaminosulfonyl ureas as herbicides ISAGRO RICERCA S.r.l. (IT) 1997-05-02 EP disclosed