SCHEMBL8901744

SCHEMBL8901744

CC(C)(C)[Si](C)(C)OC1CC(C(=O)O)(C(=O)O)CC(O[Si](C)(C)C(C)(C)C)C1O

nearest known ligand 0.38

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
PPM1D O15297 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3177924 0.85 PPM1D (0.37) PPM1D
SCHEMBL5205218 0.81 PPM1D (0.42) PPM1D
SCHEMBL8537571 0.78 PPM1D (0.46) PPM1D
SCHEMBL9010539 0.76 MMP2 (0.40) PPM1D
SCHEMBL8540123 0.73 PPM1D (0.36) PPM1D
SCHEMBL8903439 0.73 PPM1D (0.36) PPM1D
SCHEMBL8373765 0.73 PPM1D (0.36) PPM1D
SCHEMBL24080108 0.72 APLNR (0.37) PPM1D
SCHEMBL28576304 0.72 APLNR (0.37) PPM1D
SCHEMBL24080112 0.72 APLNR (0.37) PPM1D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5597932-A Intermediate for the preparation of 19-nor vitamin D compounds WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 1997-01-28 US disclosed
US-5536713-A OSTEOPOROSIS WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 1996-07-16 US disclosed