Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 6/20 | 0.41 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.39 |
| ▸ | DPP8 | Q6V1X1 | 4/20 | 0.38 |
| ▸ | DPP9 | Q86TI2 | 4/20 | 0.38 |
| ▸ | FAP | Q12884 | 1/20 | 0.38 |
| ▸ | PRCP | P42785 | 2/20 | 0.38 |
| ▸ | SCN4A | P35499 | 1/20 | 0.37 |
| ▸ | CTSC | P53634 | 1/20 | 0.34 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | ARG1 | P05089 | 1/20 | 0.33 |
| ▸ | ARG2 | P78540 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | NOS2 | P35228 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8540220 | 1.00 | DPP4 (0.41) | DPP4DPP7DPP8DPP9FAP | |
| SCHEMBL4629917 | 0.73 | CA1 (0.41) | DPP4FAPKDM4E | |
| SCHEMBL3332602 | 0.70 | SCN4A (0.48) | DPP4DPP7DPP8DPP9PRCP | |
| SCHEMBL3330098 | 0.70 | SCN4A (0.48) | DPP4DPP7DPP8DPP9PRCP | |
| SCHEMBL3673723 | 0.70 | SCN4A (0.48) | DPP4DPP7DPP8DPP9PRCP | |
| SCHEMBL953074 | 0.69 | SCN4A (0.47) | DPP4DPP7PRCPSCN4AHTR2C | |
| SCHEMBL17676964 | 0.69 | SCN4A (0.47) | DPP7PRCPSCN4AHTR2CHTR2B | |
| SCHEMBL12348733 | 0.69 | PRCP (0.46) | DPP4DPP7DPP8DPP9FAP | |
| Hydrochloric Acid SCHEMBL3636670 | 0.69 | SCN4A (0.50) | DPP4DPP7PRCPSCN4AHTR2C | |
| SCHEMBL3633992 | 0.69 | SCN4A (0.47) | DPP4DPP7PRCPSCN4AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1095843-C | 1-methylcarbapenem derivatives | SANKYO CO (JP) | 2002-12-11 | — | — | CN | disclosed |
| CN-1209130-A | 1-methylcarbapenem derivatives | SANKYO CO (JP) | 1999-02-24 | — | — | CN | disclosed |
| EP-0882728-A1 | 1-METHYLCARBAPENEM DERIVATIVES | SANKYO COMPANY LIMITED (JP) | 1998-12-09 | — | — | EP | disclosed |