Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC9 | O60706 | 5/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 11/20 | 0.40 |
| ▸ | KCNE1 | P15382 | 3/20 | 0.36 |
| ▸ | KCNQ1 | P51787 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | KCND3 | Q9UK17 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8540119 | 0.91 | ABCC9 (0.39) | ABCC9ABCB1 | |
| SCHEMBL8537451 | 0.89 | ABCC9 (0.41) | ABCC9ABCB1 | |
| SCHEMBL8542064 | 0.89 | ABCB1 (0.41) | ABCC9ABCB1 | |
| SCHEMBL8535488 | 0.87 | ABCC9 (0.47) | ABCC9ABCB1 | |
| SCHEMBL8537349 | 0.82 | ABCC9 (0.41) | ABCC9ABCB1KCNE1KCNQ1 | |
| SCHEMBL8539815 | 0.81 | ABCB1 (0.43) | ABCC9ABCB1 | |
| SCHEMBL8535842 | 0.81 | ABCC9 (0.43) | ABCC9ABCB1 | |
| SCHEMBL8536420 | 0.80 | ABCC9 (0.42) | ABCC9ABCB1 | |
| Water SCHEMBL8539489 | 0.80 | ABCC9 (0.42) | ABCC9ABCB1 | |
| SCHEMBL8535237 | 0.80 | ABCC9 (0.42) | ABCC9ABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0677519-A1 | CHROMAN DERIVATIVE AND MEDICINAL USE THEREOF | Japan Tobacco Inc. (JP) | 1995-10-18 | — | — | EP | claimed |
| US-5719155-A | CARDIOVASCULAR DISORDERS | JAPAN TOBACCO INC. (JP) | 1998-02-17 | — | — | US | disclosed |
| EP-0677519-A1 | CHROMAN DERIVATIVE AND MEDICINAL USE THEREOF | Japan Tobacco Inc. (JP) | 1995-10-18 | — | — | EP | disclosed |