Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.59 |
| ▸ | PGR | P06401 | 1/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | MMP2 | P08253 | 1/20 | 0.46 |
| ▸ | HTR1B | P28222 | 4/20 | 0.46 |
| ▸ | HTR1D | P28221 | 1/20 | 0.46 |
| ▸ | FABP7 | O15540 | 3/20 | 0.45 |
| ▸ | FABP3 | P05413 | 3/20 | 0.45 |
| ▸ | FABP5 | Q01469 | 3/20 | 0.45 |
| ▸ | BCHE | P06276 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27430337 | 0.85 | ALDH1A1 (0.58) | ALDH1A1HSD17B10PGRGAAPTGS1 | |
| SCHEMBL15759427 | 0.83 | ALDH1A1 (0.56) | ALDH1A1HSD17B10PGRGAAPTGS1 | |
| Alpha-Naphthylacetate SCHEMBL29372782 | 0.83 | ALDH1A1 (0.66) | ALDH1A1HSD17B10PGRGAAPTGS1 | |
| Alpha-Naphthylacetate SCHEMBL76633 | 0.83 | ALDH1A1 (0.66) | ALDH1A1HSD17B10PGRGAAPTGS1 | |
| Alpha-Naphthylacetate SCHEMBL10751544 | 0.82 | ALDH1A1 (0.64) | ALDH1A1HSD17B10PGRGAAPTGS1 | |
| Alpha-Naphthylacetate SCHEMBL11320989 | 0.82 | ALDH1A1 (0.64) | ALDH1A1HSD17B10PGRGAAPTGS1 | |
| Alpha-Naphthylacetate SCHEMBL10751537 | 0.82 | ALDH1A1 (0.64) | ALDH1A1HSD17B10PGRGAAPTGS1 | |
| Alpha-Naphthylacetate SCHEMBL15903555 | 0.82 | ALDH1A1 (0.64) | ALDH1A1HSD17B10PGRGAAPTGS1 | |
| Alpha-Naphthylacetate SCHEMBL14715837 | 0.82 | ALDH1A1 (0.64) | ALDH1A1HSD17B10PGRGAAPTGS1 | |
| Alpha-Naphthylacetate SCHEMBL14715880 | 0.82 | ALDH1A1 (0.64) | ALDH1A1HSD17B10PGRGAAPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5719155-A | CARDIOVASCULAR DISORDERS | JAPAN TOBACCO INC. (JP) | 1998-02-17 | — | — | US | disclosed |
| EP-0677519-A1 | CHROMAN DERIVATIVE AND MEDICINAL USE THEREOF | Japan Tobacco Inc. (JP) | 1995-10-18 | — | — | EP | disclosed |