Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 15/20 | 0.59 |
| ▸ | CTSL | P07711 | 3/20 | 0.55 |
| ▸ | CTSB | P07858 | 3/20 | 0.55 |
| ▸ | PPARA | Q07869 | 2/20 | 0.55 |
| ▸ | CTSH | P09668 | 1/20 | 0.50 |
| ▸ | PPARG | P37231 | 1/20 | 0.50 |
| ▸ | CTSS | P25774 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8540381 | 1.00 | CTSK (0.59) | CTSKCTSLCTSBPPARACTSH | |
| SCHEMBL5808813 | 0.84 | CTSK (0.65) | CTSKCTSLCTSBCTSHCTSS | |
| SCHEMBL4126013 | 0.84 | PPARA (0.63) | CTSKCTSLCTSBPPARAPPARG | |
| SCHEMBL271394 | 0.84 | PPARA (0.63) | CTSKCTSLCTSBPPARAPPARG | |
| SCHEMBL2230694 | 0.84 | PPARA (0.63) | CTSKCTSLCTSBPPARAPPARG | |
| SCHEMBL28516961 | 0.84 | CTSK (0.57) | CTSKCTSLCTSBCTSH | |
| SCHEMBL8615711 | 0.84 | PPARA (0.69) | CTSKPPARAPPARGCTSSL3MBTL1 | |
| SCHEMBL4821212 | 0.84 | MAPT (0.66) | CTSKCTSLCTSB | |
| SCHEMBL8311926 | 0.84 | CTSK (0.56) | CTSKCTSLCTSBCTSH | |
| SCHEMBL8567696 | 0.83 | PPARA (0.54) | CTSKCTSLCTSBPPARAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0820445-A1 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | Merck & Co., Inc. (US) | 1998-01-28 | — | — | EP | disclosed |