SCHEMBL8540432

SCHEMBL8540432

CONc1c[nH]cn1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL26933944 0.71
SCHEMBL27676677 0.69
SCHEMBL445017 0.65 MAPT (0.48)
Hydrochloric Acid SCHEMBL7540285 0.64 TAS2R38 (0.33)
SCHEMBL28327064 0.64
SCHEMBL1145851 0.64
SCHEMBL27624078 0.63 HPGD (0.36)
Hydrochloric Acid SCHEMBL28230827 0.62
SCHEMBL2154177 0.61 HSD17B10 (0.39)
SCHEMBL69204 0.61

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0529680-B1 Intermediates, their production and their use for preparing alpha-unsaturated amines TAKEDA CHEMICAL INDUSTRIES LTD (JP) 1998-05-13 EP claimed
EP-0302389-B1 Alpha-unsaturated amines, their production and use TAKEDA CHEMICAL INDUSTRIES LTD (JP) 1993-12-22 EP claimed