Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 1/20 | 0.33 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.31 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.30 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL313587 | 0.72 | GSR (0.40) | GSRDPP7DPP4DPP8DPP9 | |
| SCHEMBL997560 | 0.66 | GSR (0.52) | GSRDPP7DPP4DPP8DPP9 | |
| SCHEMBL29075853 | 0.66 | GSR (0.52) | GSRDPP7DPP4DPP8DPP9 | |
| SCHEMBL1537223 | 0.66 | GSR (0.52) | GSRDPP7DPP4DPP8DPP9 | |
| SCHEMBL1408946 | 0.64 | GSR (0.50) | GSRDPP7DPP4DPP8DPP9 | |
| SCHEMBL5037167 | 0.64 | GSR (0.50) | GSRDPP7DPP4DPP8DPP9 | |
| SCHEMBL1408948 | 0.64 | GSR (0.50) | GSRDPP7DPP4DPP8DPP9 | |
| SCHEMBL28747119 | 0.64 | GSR (0.50) | GSRDPP7DPP4DPP8DPP9 | |
| SCHEMBL20475718 | 0.64 | GSR (0.47) | GSRDPP7DPP4DPP8DPP9 | |
| SCHEMBL7899768 | 0.64 | GSR (0.47) | GSRDPP7DPP4DPP8DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0504064-B1 | Novel thrombin inhibitors | MERRELL PHARMA INC (US) | 1998-05-13 | — | — | EP | disclosed |
| US-5498779-A | ANTICOAGULANTS AND TREATMENT OF ASTHMA | MERRELL PHARMACEUTICALS INC. (US) | 1996-03-12 | — | — | US | disclosed |
| US-5391705-A | Anticoagulants, treats thrombophlebitis, coronary thrombosis and asthma | MERRELL DOW PHARMACEUTICALS INC. (US) | 1995-02-21 | — | — | US | disclosed |
| EP-0504064-A1 | Novel thrombin inhibitors | MERRELL PHARMACEUTICALS INC. (US) | 1992-09-16 | — | — | EP | disclosed |