SCHEMBL1408946

SCHEMBL1408946

NCCC[C@H](N)C(=O)ON

nearest known ligand 0.50

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
GSR P00390 1/20 0.50
DPP7 Q9UHL4 8/20 0.40
DPP4 P27487 3/20 0.40
DPP8 Q6V1X1 3/20 0.38
DPP9 Q86TI2 3/20 0.38
CPB2 Q96IY4 2/20 0.38
GNAI3 P08754 1/20 0.36
GNAO1 P09471 1/20 0.36
GNAI1 P63096 1/20 0.36
RNPEP Q9H4A4 1/20 0.34
CYP1A2 P05177 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1408948 1.00 GSR (0.50) GSRDPP7DPP4DPP8DPP9
SCHEMBL4352729 0.93 GSR (0.59) GSRDPP7DPP4DPP8DPP9
SCHEMBL16192990 0.93 GSR (0.59) GSRDPP7DPP4DPP8DPP9
SCHEMBL169864 0.93 GSR (0.59) GSRDPP7DPP4DPP8DPP9
SCHEMBL14811921 0.91 GSR (0.57) GSRDPP7DPP4DPP8DPP9
SCHEMBL29075853 0.88 GSR (0.52) GSRDPP7DPP4DPP8DPP9
SCHEMBL1537223 0.88 GSR (0.52) GSRDPP7DPP4DPP8DPP9
SCHEMBL997560 0.88 GSR (0.52) GSRDPP7DPP4DPP8DPP9
SCHEMBL680614 0.84 GSR (0.59) GSRDPP7DPP4DPP8DPP9
SCHEMBL9902389 0.83 GSR (0.47) GSRDPP7DPP4DPP8DPP9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1423137-B1 LIPOPEPTIDE STEREOISOMERS, METHODS FOR PREPARING SAME, AND USEFUL INTERMEDIATES CUBIST PHARM INC (US) 2009-04-29 EP claimed
EP-1423137-A4 LIPOPEPTIDE STEREOISOMERS, METHODS FOR PREPARING SAME, AND USEFUL INTERMEDIATES CUBIST PHARM INC (US) 2005-11-30 EP claimed
EP-1423137-A2 LIPOPEPTIDE STEREOISOMERS, METHODS FOR PREPARING SAME, AND USEFUL INTERMEDIATES Cubist Pharmaceuticals, Inc. (US) 2004-06-02 EP claimed
US-20030096948-A1 Lipopeptide stereoisomers, methods for preparing same, and useful intermediates ADOLOR CORPORATION 2003-05-22 US claimed
WO-2003017924-A2 LIPOPEPTIDE STEREOISOMERS, METHODS FOR PREPARING SAME, AND USEFUL INTERMEDIATES CUBIST PHARMACEUTICALS, INC. (US) 2003-03-06 WO claimed
EP-4610269-A1 UROKINASE PLASMINOGEN ACTIVATOR SURFACE RECEPTOR (UPAR) LIGANDS FOR DIAGNOSTIC OR THERAPEUTIC USE 3B Pharmaceuticals GmbH (DE) 2025-09-03 EP disclosed
US-20230111132-A1 STABILIZATION OF MHC COMPLEXES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2023-04-13 US disclosed
EP-4081254-A1 STABILIZATION OF MHC COMPLEXES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2022-11-02 EP disclosed
WO-2021133742-A1 STABILIZATION OF MHC COMPLEXES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2021-07-01 WO disclosed
EP-2298790-A1 Daptomycin analogs as antibacterial agents Cubist Pharmaceuticals, Inc. (US) 2011-03-23 EP disclosed
EP-2295444-A2 Lipopeptides as antibacterial agents Cubist Pharmaceutical Inc. (US) 2011-03-16 EP disclosed
EP-1423137-B1 LIPOPEPTIDE STEREOISOMERS, METHODS FOR PREPARING SAME, AND USEFUL INTERMEDIATES CUBIST PHARM INC (US) 2009-04-29 EP disclosed
EP-1246838-A1 LIPOPEPTIDES AS ANTIBACTERIAL AGENTS Cubist Pharmaceuticals, Inc. (US) 2002-10-09 EP disclosed
EP-1240181-A2 DAPTOMYCIN ANALOGS AS ANTIBACTERIAL AGENTS Cubist Pharmaceuticals, Inc. (US) 2002-09-18 EP disclosed
US-20020058785-A1 Novel lipopeptides as antibacterial agents MERCK SHARP & DOHME CORP. 2002-05-16 US disclosed
US-20020025924-A1 Novel lipopeptides as antibacterial agents MERCK SHARP & DOHME CORP. 2002-02-28 US disclosed
WO-2001044272-A2 DAPTOMYCIN ANALOGS AS ANTIBACTERIAL AGENTS CUBIST PHARMACEUTICALS, INC. (US) 2001-06-21 WO disclosed
WO-2001044274-A1 LIPOPEPTIDES AS ANTIBACTERIAL AGENTS CUBIST PHARMACEUTICALS, INC. (US) 2001-06-21 WO disclosed
US-5914313-A ANTIBIOTICS MERCK & CO., INC. (US) 1999-06-22 US disclosed
US-5741775-A ANTIBIOTIC AND ANTIFUNGAL AGENTS MERCK & CO., INC. (US) 1998-04-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020058785-A1 Novel lipopeptides as antibacterial agents CLPTM1, NGLY1, VIP GSR 3234/4885DPP7 456/4885DPP4 437/4885
US-20030096948-A1 Lipopeptide stereoisomers, methods for preparing same, and useful intermediates LSS, NGLY1, RPN1 GSR 3978/4885DPP7 252/4885DPP4 491/4885
US-20020025924-A1 Novel lipopeptides as antibacterial agents CLPTM1, NGLY1, VIP GSR 3234/4885DPP7 456/4885DPP4 437/4885
US-20230111132-A1 STABILIZATION OF MHC COMPLEXES MICA, CD74, HLA-DRB1 GSR 2408/4885DPP7 3085/4885DPP4 3871/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.