Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.58 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29084422 | 0.83 | TSHR (0.46) | TSHRTHRBALDH1A1 | |
| SCHEMBL3319370 | 0.82 | TSHR (0.75) | TSHRTHRBALDH1A1CA1CA2 | |
| SCHEMBL22138 | 0.82 | TSHR (0.53) | TSHRTHRBALDH1A1 | |
| SCHEMBL10716986 | 0.81 | TSHR (0.52) | TSHRTHRBALDH1A1 | |
| Ammonia Solution, Strong SCHEMBL18138985 | 0.81 | TSHR (0.52) | TSHRTHRBALDH1A1 | |
| SCHEMBL20001266 | 0.81 | TSHR (0.72) | TSHRTHRBALDH1A1CA1CA2 | |
| SCHEMBL28748147 | 0.80 | TSHR (0.47) | TSHRTHRBALDH1A1 | |
| SCHEMBL2212633 | 0.79 | TSHR (0.50) | TSHRTHRBALDH1A1 | |
| SCHEMBL4526188 | 0.79 | TSHR (0.69) | TSHRTHRBALDH1A1 | |
| SCHEMBL31059270 | 0.79 | TSHR (0.69) | TSHRTHRBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103068411-B | Emophysematous therapeutic agent | TERUMO CORP. (JP) | 2016-01-20 | — | — | CN | disclosed |
| CN-103068411-A | Therapeutic agent for pulmonary emphysema | TERUMO CORP | 2013-04-24 | — | — | CN | disclosed |
| US-5804354-A | SULFONATED POLYANILINES | FUJITSU LIMITED (JP) | 1998-09-08 | — | — | US | disclosed |