Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC9 | O60706 | 8/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 10/20 | 0.38 |
| ▸ | ABCC8 | Q09428 | 2/20 | 0.35 |
| ▸ | KCNJ11 | Q14654 | 2/20 | 0.35 |
| ▸ | KCNJ8 | Q15842 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8537349 | 0.91 | ABCC9 (0.41) | ABCC9ABCB1 | |
| SCHEMBL8535817 | 0.90 | ABCC9 (0.41) | ABCC9ABCB1 | |
| SCHEMBL8536345 | 0.89 | ABCC9 (0.40) | ABCC9ABCB1CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL8535230 | 0.89 | ABCC9 (0.42) | ABCC9ABCB1 | |
| SCHEMBL8538266 | 0.89 | ABCC9 (0.40) | ABCC9ABCB1 | |
| SCHEMBL8537101 | 0.89 | ABCB1 (0.41) | ABCC9ABCB1 | |
| SCHEMBL8539533 | 0.89 | ABCC9 (0.40) | ABCC9ABCB1 | |
| SCHEMBL8535712 | 0.89 | ABCC9 (0.41) | ABCC9ABCB1 | |
| SCHEMBL8540184 | 0.88 | ABCC9 (0.39) | ABCC9ABCB1CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL8539755 | 0.88 | ABCC9 (0.39) | ABCC9ABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5719155-A | CARDIOVASCULAR DISORDERS | JAPAN TOBACCO INC. (JP) | 1998-02-17 | — | — | US | claimed |
| EP-0677519-A1 | CHROMAN DERIVATIVE AND MEDICINAL USE THEREOF | Japan Tobacco Inc. (JP) | 1995-10-18 | — | — | EP | claimed |
| US-5719155-A | CARDIOVASCULAR DISORDERS | JAPAN TOBACCO INC. (JP) | 1998-02-17 | — | — | US | disclosed |
| EP-0677519-A1 | CHROMAN DERIVATIVE AND MEDICINAL USE THEREOF | Japan Tobacco Inc. (JP) | 1995-10-18 | — | — | EP | disclosed |