Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8540106 | 0.99 | AGTR1 (0.62) | AGTR1AGTR2 | |
| SCHEMBL8540003 | 0.99 | AGTR1 (0.62) | AGTR1AGTR2 | |
| SCHEMBL8541636 | 0.94 | AGTR1 (0.55) | AGTR1AGTR2 | |
| Cl-329167 SCHEMBL4111462 | 0.91 | AGTR1 (0.76) | AGTR1AGTR2 | |
| SCHEMBL9160007 | 0.89 | — | — | |
| SCHEMBL9160015 | 0.89 | — | — | |
| SCHEMBL9402007 | 0.89 | — | — | |
| SCHEMBL9379473 | 0.88 | — | — | |
| SCHEMBL9402071 | 0.87 | PDE4A (0.64) | — | |
| SCHEMBL9295920 | 0.87 | AGTR1 (0.53) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0497150-B1 | Angiotensin II receptor blocking 2,3,6-substituted quinazolones | AMERICAN CYANAMID CO (US) | 1998-03-18 | — | — | EP | claimed |
| EP-0497150-A1 | Angiotensin II receptor blocking 2,3,6-substituted quinazolones | AMERICAN CYANAMID COMPANY (US) | 1992-08-05 | — | — | EP | claimed |
| EP-0497150-B1 | Angiotensin II receptor blocking 2,3,6-substituted quinazolones | AMERICAN CYANAMID CO (US) | 1998-03-18 | — | — | EP | disclosed |
| US-5405849-A | Treating hypertension, congestive heart failure | AMERICAN CYANAMID COMPANY (US) | 1995-04-11 | — | — | US | disclosed |
| US-5290780-A | Hypotensive agents; congestive heart failure | AMERICAN CYANAMID CO. (US) | 1994-03-01 | — | — | US | disclosed |
| EP-0497150-A1 | Angiotensin II receptor blocking 2,3,6-substituted quinazolones | AMERICAN CYANAMID COMPANY (US) | 1992-08-05 | — | — | EP | disclosed |