Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
| ▸ | SCN1A | P35498 | 1/20 | 0.40 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.40 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8537818 | 1.00 | MAPK1 (0.50) | MAPK1CYP3A4CYP2D6MEN1KMT2A | |
| SCHEMBL19784271 | 0.74 | MEN1 (0.39) | MAPK1CYP3A4MEN1KMT2ALMNA | |
| SCHEMBL25954641 | 0.74 | MEN1 (0.39) | MAPK1CYP3A4MEN1KMT2ALMNA | |
| SCHEMBL125445 | 0.74 | MEN1 (0.39) | MAPK1CYP3A4MEN1KMT2ALMNA | |
| SCHEMBL9199389 | 0.73 | MAPK1 (0.53) | MAPK1CYP3A4CYP2D6MEN1KMT2A | |
| SCHEMBL20702256 | 0.73 | EPHX1 (0.44) | MAPK1CYP3A4CYP2D6LMNACYP2C19 | |
| SCHEMBL6495554 | 0.70 | MAPK1 (0.53) | MAPK1CYP3A4CYP2D6MEN1KMT2A | |
| SCHEMBL16309629 | 0.68 | CYP3A4 (0.77) | MAPK1CYP3A4CYP2D6MEN1KMT2A | |
| SCHEMBL19419092 | 0.67 | MEN1 (0.45) | MEN1KMT2ALMNACYP2C19L3MBTL1 | |
| SCHEMBL12393860 | 0.67 | SIRT1 (0.49) | MAPK1CYP3A4MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0358154-B1 | Novel cyclobutane derivative and process for producing same | NIPPON KAYAKU KK (JP) | 1998-12-02 | — | — | EP | disclosed |
| US-5250697-A | Drugs, perfumes, reagents, intermediates for viraicides | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1993-10-05 | — | — | US | disclosed |
| EP-0444597-A1 | Novel cyclobutane derivative | Nippon Kayaku Kabushiki Kaisha (JP) | 1991-09-04 | — | — | EP | disclosed |