Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 4/20 | 0.62 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.51 |
| ▸ | OGT | O15294 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.42 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8541679 | 1.00 | GRIN2B (0.62) | GRIN2BKCNH2OGTALDH1A1ATM | |
| SCHEMBL8547979 | 1.00 | GRIN2B (0.62) | GRIN2BKCNH2OGTALDH1A1ATM | |
| SCHEMBL8547850 | 1.00 | GRIN2B (0.62) | GRIN2BKCNH2OGTALDH1A1ATM | |
| Hydrochloric Acid SCHEMBL8548360 | 0.94 | GRIN2B (0.55) | GRIN2BKCNH2OGTALDH1A1ATM | |
| Hydrochloric Acid SCHEMBL8548193 | 0.94 | GRIN2B (0.55) | GRIN2BKCNH2OGTALDH1A1ATM | |
| SCHEMBL8547674 | 0.93 | GRIN2B (0.55) | GRIN2BKCNH2OGTMAOAMAOB | |
| SCHEMBL8872102 | 0.93 | GRIN2B (0.55) | GRIN2BKCNH2OGTMAOAMAOB | |
| SCHEMBL8546412 | 0.88 | GRIN2B (0.50) | GRIN2BKCNH2OGTMAOAMAOB | |
| SCHEMBL8548698 | 0.86 | GRIN2B (0.47) | GRIN2BKCNH2ALDH1A1ATMMEN1 | |
| SCHEMBL8547693 | 0.86 | GRIN2B (0.47) | GRIN2BKCNH2ALDH1A1ATMMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0709384-B1 | Benzylpiperidine derivatives having high affinity for binding sites of aminoacid receptors | MERCK PATENT GMBH (DE) | 1998-12-23 | — | — | EP | claimed |
| US-5698553-A | Benzylpiperidine derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1997-12-16 | — | — | US | claimed |
| EP-0709384-A1 | Benzylpiperidine derivatives having high affinity for binding sites of aminoacid receptors | MERCK PATENT GmbH (DE) | 1996-05-01 | — | — | EP | claimed |
| JP-8225569-A | — | — | None | — | — | JP | disclosed |
| EP-0709384-B1 | Benzylpiperidine derivatives having high affinity for binding sites of aminoacid receptors | MERCK PATENT GMBH (DE) | 1998-12-23 | — | — | EP | disclosed |
| US-5698553-A | Benzylpiperidine derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1997-12-16 | — | — | US | disclosed |
| JP-H08225569-A | BENZYLPIPERIDINE DERIVATIVE | MERCK PATENT GMBH | 1996-09-03 | — | — | JP | disclosed |
| EP-0709384-A1 | Benzylpiperidine derivatives having high affinity for binding sites of aminoacid receptors | MERCK PATENT GmbH (DE) | 1996-05-01 | — | — | EP | disclosed |