Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 8/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.40 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.40 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.39 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.39 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.39 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.39 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.39 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8547693 | 1.00 | GRIN2B (0.47) | GRIN2BMEN1KMT2AALDH1A1ATM | |
| SCHEMBL8544371 | 1.00 | GRIN2B (0.47) | GRIN2BMEN1KMT2AALDH1A1ATM | |
| SCHEMBL8542863 | 0.93 | GRIN2B (0.47) | GRIN2BCARM1PRMT6KCNH2GRIN2D | |
| SCHEMBL8541679 | 0.86 | GRIN2B (0.62) | GRIN2BMEN1KMT2AALDH1A1ATM | |
| SCHEMBL8547979 | 0.86 | GRIN2B (0.62) | GRIN2BMEN1KMT2AALDH1A1ATM | |
| SCHEMBL8547850 | 0.86 | GRIN2B (0.62) | GRIN2BMEN1KMT2AALDH1A1ATM | |
| SCHEMBL8540531 | 0.86 | GRIN2B (0.62) | GRIN2BMEN1KMT2AALDH1A1ATM | |
| SCHEMBL8544941 | 0.85 | GRIN2B (0.51) | GRIN2BMEN1KMT2AALDH1A1ATM | |
| SCHEMBL8543097 | 0.85 | GRIN2B (0.51) | GRIN2BMEN1KMT2AALDH1A1ATM | |
| SCHEMBL8544937 | 0.85 | GRIN2B (0.51) | GRIN2BMEN1KMT2AALDH1A1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0709384-B1 | Benzylpiperidine derivatives having high affinity for binding sites of aminoacid receptors | MERCK PATENT GMBH (DE) | 1998-12-23 | — | — | EP | disclosed |
| US-5698553-A | Benzylpiperidine derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1997-12-16 | — | — | US | disclosed |
| EP-0709384-A1 | Benzylpiperidine derivatives having high affinity for binding sites of aminoacid receptors | MERCK PATENT GmbH (DE) | 1996-05-01 | — | — | EP | disclosed |