Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | EGFR | P00533 | 3/20 | 0.49 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.49 |
| ▸ | BRAF | P15056 | 1/20 | 0.48 |
| ▸ | KDR | P35968 | 1/20 | 0.48 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.48 |
| ▸ | TNNI3K | Q59H18 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | APP | P05067 | 2/20 | 0.43 |
| ▸ | AURKA | O14965 | 1/20 | 0.43 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8541083 | 0.94 | TSHR (0.49) | TSHRRAB9ANPC1L3MBTL1EGFR | |
| SCHEMBL8544690 | 0.90 | RAB9A (0.52) | TSHRRAB9ANPC1L3MBTL1EGFR | |
| Hydrochloric Acid SCHEMBL27889646 | 0.86 | RAB9A (0.49) | TSHRRAB9ANPC1L3MBTL1EGFR | |
| SCHEMBL8543530 | 0.86 | RAB9A (0.54) | TSHRRAB9ANPC1L3MBTL1EGFR | |
| SCHEMBL8545631 | 0.85 | MAPK14 (0.52) | TSHRRAB9ANPC1L3MBTL1EGFR | |
| SCHEMBL8547515 | 0.83 | AURKA (0.46) | SIRT2TAAR1AURKARPS6KB1IDO1 | |
| SCHEMBL8548739 | 0.81 | RAB9A (0.69) | TSHRRAB9ANPC1L3MBTL1EGFR | |
| SCHEMBL8544270 | 0.81 | RAB9A (0.57) | TSHRRAB9ANPC1L3MBTL1EGFR | |
| SCHEMBL8546082 | 0.81 | RAB9A (0.54) | TSHRRAB9ANPC1L3MBTL1EGFR | |
| SCHEMBL8547183 | 0.81 | RAB9A (0.54) | TSHRRAB9ANPC1L3MBTL1EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0326329-B1 | Quinazoline derivatives useful as insecticides. | DOW AGROSCIENCES LLC (US) | 1998-10-28 | — | — | EP | disclosed |