Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 5/20 | 0.47 |
| ▸ | CDC25B | P30305 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 3/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL995737 | 0.90 | TSHR (0.74) | TSHRALDH1A1HSD17B10KDM4EKMT2A | |
| SCHEMBL8589676 | 0.82 | CA1 (0.51) | TSHRALDH1A1HSD17B10KDM4EKMT2A | |
| Diethyl Phthalate SCHEMBL27896497 | 0.81 | TSHR (0.84) | TSHRALDH1A1HSD17B10KDM4EKMT2A | |
| SCHEMBL23078360 | 0.78 | TSHR (0.59) | TSHRALDH1A1HSD17B10KMT2ACDC25B | |
| SCHEMBL2458287 | 0.78 | TSHR (0.65) | TSHRALDH1A1HSD17B10KDM4EKMT2A | |
| Diethyl Phthalate SCHEMBL29404255 | 0.77 | TSHR (1.00) | TSHRALDH1A1HSD17B10KDM4EKMT2A | |
| Diethyl Phthalate SCHEMBL5306972 | 0.77 | TSHR (1.00) | TSHRALDH1A1HSD17B10KDM4EKMT2A | |
| Diethyl Phthalate SCHEMBL22296 | 0.77 | TSHR (1.00) | TSHRALDH1A1HSD17B10KDM4EKMT2A | |
| SCHEMBL1656703 | 0.77 | TSHR (0.63) | TSHRALDH1A1HSD17B10KDM4EKMT2A | |
| SCHEMBL8890720 | 0.77 | TSHR (0.56) | TSHRALDH1A1HSD17B10KDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0574418-B1 | ARYL SULPHONYL UREA COMPOUNDS, A METHOD OF PREPARING THEM, AND THEIR USE AS HERBICIDES AND GROWTH REGULATORS | HOECHST SCHERING AGREVO GMBH (DE) | 1998-11-11 | — | — | EP | disclosed |
| US-5688745-A | Arylsulfonylureas and their use as herbicides and growth regulators | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-11-18 | — | — | US | disclosed |
| EP-0574418-A1 | ARYL SULPHONYL UREA COMPOUNDS, A METHOD OF PREPARING THEM, AND THEIR USE AS HERBICIDES AND GROWTH REGULATORS | Hoechst Schering AgrEvo GmbH (DE) | 1993-12-22 | — | — | EP | disclosed |
| WO-1992013845-A1 | ARYL SULPHONYL UREA COMPOUNDS, A METHOD OF PREPARING THEM, AND THEIR USE AS HERBICIDES AND GROWTH REGULATORS | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-08-20 | — | — | WO | disclosed |