Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 7/20 | 0.36 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.35 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.33 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.33 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7502685 | 0.83 | HIF1A (0.44) | HIF1AKAT6APARP14PARP10MAOB | |
| SCHEMBL7741766 | 0.81 | HIF1A (0.43) | HIF1AKAT6APARP14PARP10 | |
| SCHEMBL7741767 | 0.81 | HIF1A (0.43) | HIF1AKAT6APARP14PARP10 | |
| SCHEMBL7504398 | 0.79 | HIF1A (0.40) | HIF1APARP14PARP10 | |
| SCHEMBL7504767 | 0.78 | PARP14 (0.36) | HIF1AKAT6ACRBNPARP14PARP10 | |
| SCHEMBL6703061 | 0.75 | HIF1A (0.39) | HIF1AKDM4E | |
| SCHEMBL8542626 | 0.75 | RAB9A (0.33) | HIF1AKDM4ESMN1; SMN2L3MBTL1 | |
| SCHEMBL7741770 | 0.75 | KAT6A (0.33) | HIF1AKAT6ACRBNPARP14PARP10 | |
| SCHEMBL7492764 | 0.74 | HIF1A (0.39) | HIF1ASMN1; SMN2L3MBTL1 | |
| SCHEMBL7741988 | 0.74 | HIF1A (0.31) | HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0865424-A1 | PESTICIDES | Novartis AG (CH) | 1998-09-23 | — | — | EP | disclosed |
| WO-1997020809-A1 | PESTICIDES | NOVARTIS AG (CH) | 1997-06-12 | — | — | WO | disclosed |