Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 4/20 | 0.37 |
| ▸ | CA1 | P00915 | 4/20 | 0.37 |
| ▸ | CA2 | P00918 | 4/20 | 0.37 |
| ▸ | CA4 | P22748 | 4/20 | 0.37 |
| ▸ | CA6 | P23280 | 4/20 | 0.37 |
| ▸ | CA5A | P35218 | 4/20 | 0.37 |
| ▸ | CA7 | P43166 | 4/20 | 0.37 |
| ▸ | CA9 | Q16790 | 4/20 | 0.37 |
| ▸ | CA13 | Q8N1Q1 | 4/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.37 |
| ▸ | CA5B | Q9Y2D0 | 4/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | CA3 | P07451 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8538511 | 0.97 | SLC9A1 (0.43) | SLC9A1CA12CA1CA2CA4 | |
| SCHEMBL8542836 | 0.96 | SLC9A1 (0.43) | SLC9A1CA12CA1CA2CA4 | |
| SCHEMBL8536912 | 0.96 | SLC9A1 (0.43) | SLC9A1CA12CA1CA2CA4 | |
| SCHEMBL8538271 | 0.94 | SLC9A1 (0.46) | SLC9A1 | |
| SCHEMBL8542782 | 0.84 | SLC9A1 (0.40) | SLC9A1 | |
| SCHEMBL8536959 | 0.84 | CA12 (0.39) | CA12CA1CA2CA4CA6 | |
| SCHEMBL6719348 | 0.83 | SLC9A1 (0.57) | SLC9A1 | |
| SCHEMBL8542870 | 0.81 | CA12 (0.41) | CA12CA1CA2CA4CA6 | |
| SCHEMBL7068651 | 0.81 | SLC9A1 (0.73) | SLC9A1 | |
| SCHEMBL8537872 | 0.80 | CA12 (0.43) | CA12CA1CA2CA4CA6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5744641-A | Sulfonyl- or sulfinylbenzoylguanidine derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-04-28 | — | — | US | disclosed |