Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 2/20 | 0.33 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.32 |
| ▸ | KCNE1 | P15382 | 3/20 | 0.32 |
| ▸ | KCNQ1 | P51787 | 3/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8541314 | 1.00 | OPRL1 (0.33) | OPRL1ABCC9KCNE1KCNQ1TRPV1 | |
| SCHEMBL8541325 | 1.00 | OPRL1 (0.33) | OPRL1ABCC9KCNE1KCNQ1TRPV1 | |
| SCHEMBL8535803 | 0.85 | ABCC9 (0.43) | ABCC9 | |
| SCHEMBL8541389 | 0.84 | MAPT (0.39) | MEN1NPC1RAB9AKMT2A | |
| SCHEMBL8541397 | 0.84 | MAPT (0.39) | MEN1NPC1RAB9AKMT2A | |
| SCHEMBL8541404 | 0.84 | MAPT (0.39) | MEN1NPC1RAB9AKMT2A | |
| SCHEMBL8539395 | 0.80 | TRPV1 (0.36) | ABCC9KCNE1KCNQ1TRPV1 | |
| SCHEMBL8539369 | 0.80 | TRPV1 (0.36) | ABCC9KCNE1KCNQ1TRPV1 | |
| SCHEMBL8539386 | 0.80 | TRPV1 (0.36) | ABCC9KCNE1KCNQ1TRPV1 | |
| SCHEMBL8536391 | 0.80 | TRPV1 (0.39) | KCNE1KCNQ1TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0677519-A1 | CHROMAN DERIVATIVE AND MEDICINAL USE THEREOF | Japan Tobacco Inc. (JP) | 1995-10-18 | — | — | EP | claimed |
| US-5719155-A | CARDIOVASCULAR DISORDERS | JAPAN TOBACCO INC. (JP) | 1998-02-17 | — | — | US | disclosed |
| EP-0677519-A1 | CHROMAN DERIVATIVE AND MEDICINAL USE THEREOF | Japan Tobacco Inc. (JP) | 1995-10-18 | — | — | EP | disclosed |