Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9529685 | 0.91 | AGTR1 (0.54) | AGTR1AGTR2 | |
| SCHEMBL6006189 | 0.89 | AGTR1 (0.52) | AGTR1AGTR2 | |
| SCHEMBL9529104 | 0.89 | AGTR1 (0.52) | AGTR1AGTR2 | |
| SCHEMBL9528396 | 0.88 | AGTR1 (0.51) | AGTR1AGTR2 | |
| SCHEMBL6006204 | 0.88 | AGTR1 (0.53) | AGTR1AGTR2 | |
| SCHEMBL6006200 | 0.88 | AGTR1 (0.49) | AGTR1AGTR2 | |
| SCHEMBL6004656 | 0.87 | AGTR1 (0.51) | AGTR1AGTR2 | |
| SCHEMBL6005990 | 0.87 | AGTR1 (0.49) | AGTR1AGTR2 | |
| SCHEMBL9530074 | 0.87 | AGTR1 (0.49) | AGTR1AGTR2 | |
| SCHEMBL6007190 | 0.87 | AGTR1 (0.51) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0527851-B1 | 1H-SUBSTITUTED-1,2,4-TRIAZOLE COMPOUNDS FOR TREATMENT OF CARDIOVASCULAR DISORDERS | SEARLE & CO (US) | 1998-12-23 | — | — | EP | claimed |
| EP-0527851-B1 | 1H-SUBSTITUTED-1,2,4-TRIAZOLE COMPOUNDS FOR TREATMENT OF CARDIOVASCULAR DISORDERS | SEARLE & CO (US) | 1998-12-23 | — | — | EP | disclosed |