SCHEMBL8541985

SCHEMBL8541985

CC[C@H](C)[C@H](Cl)C(=O)Oc1ccc(-c2ccc(OCC(F)(F)OC(F)(F)C(F)(F)OC(F)(F)C(F)(F)C(F)(F)C(F)(F)F)cc2)cc1

nearest known ligand 0.33

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
DGAT1 O75907 6/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8545570 0.91 DGAT1 (0.34) DGAT1
SCHEMBL8540081 0.86 DGAT1 (0.34) DGAT1
SCHEMBL8541990 0.83 MAPT (0.33)
SCHEMBL8545221 0.83 HDAC3 (0.33) DGAT1
SCHEMBL8547042 0.82 DGAT1 (0.35) DGAT1
SCHEMBL8546578 0.80 DGAT1 (0.32) DGAT1
SCHEMBL8542037 0.80 FFAR1 (0.36)
SCHEMBL8544724 0.80 AAK1 (0.30)
SCHEMBL8544687 0.79 CYP17A1 (0.39)
SCHEMBL8545556 0.78 AAK1 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0736078-B1 CHIRAL LIQUID CRYSTAL COMPOUNDS HAVING A PERFLUOROETHER TERMINAL PORTION MINNESOTA MINING & MFG (US) 1998-06-24 EP disclosed