Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10893492 | 0.89 | GFER (0.43) | GFERALDH1A1MEN1KMT2ARAB9A | |
| SCHEMBL11330158 | 0.85 | USP2 (0.51) | ALDH1A1MEN1KMT2AKDM4ETHRB | |
| SCHEMBL8926268 | 0.84 | GFER (0.43) | GFERALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL11417448 | 0.83 | GFER (0.51) | GFERALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL11347164 | 0.82 | MEN1 (0.46) | ALDH1A1MEN1KMT2AKDM4ETHRB | |
| SCHEMBL11653974 | 0.81 | KMT2A (0.44) | GFERALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL11593051 | 0.80 | MEN1 (0.41) | GFERALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL10997339 | 0.80 | ALDH1A1 (0.43) | GFERALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL9300167 | 0.80 | GFER (0.42) | GFERALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL11793632 | 0.80 | GFER (0.42) | GFERALDH1A1MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0745153-B1 | DISAZO DYES CONTAINING A FLUOROSULPHONYL GROUP AND USE THEREOF | ZENECA LTD (GB) | 1998-09-30 | — | — | EP | disclosed |
| US-5782934-A | Process of dyeing with disazo dyes containing a fluorosulphonyl group and use thereof | ZENECA LIMITED (GB) | 1998-07-21 | — | — | US | disclosed |