Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 1/20 | 0.55 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.53 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.51 |
| ▸ | CCR3 | P51677 | 1/20 | 0.51 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.51 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.48 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8543391 | 0.89 | F10 (0.49) | GRIN2BHRH3SIGMAR1P2RX7KCNH2 | |
| SCHEMBL8539193 | 0.87 | GRIN2B (0.54) | GRIN2BHRH3SIGMAR1CCR3HTR2A | |
| SCHEMBL8541698 | 0.86 | HRH3 (0.54) | GRIN2BHRH3SIGMAR1CCR3CARM1 | |
| SCHEMBL8540919 | 0.85 | HRH3 (0.56) | GRIN2BHRH3SIGMAR1CCR3CARM1 | |
| SCHEMBL8541622 | 0.85 | GRIN2B (0.52) | GRIN2BHRH3SIGMAR1CCR3CARM1 | |
| SCHEMBL8545094 | 0.83 | F10 (0.57) | GRIN2BSIGMAR1 | |
| SCHEMBL8539516 | 0.81 | HRH3 (0.53) | GRIN2BHRH3SIGMAR1CCR3CARM1 | |
| SCHEMBL5069468 | 0.81 | ALDH1A1 (0.59) | SIGMAR1P2RX7 | |
| SCHEMBL8546968 | 0.80 | F10 (0.57) | GRIN2B | |
| Hydrochloric Acid SCHEMBL10419172 | 0.80 | ALDH1A1 (0.52) | HRH3P2RX7KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0705258-B1 | AZOLYL-CYCLIC AMINE DERIVATIVES WITH IMMUNOMODULATORY ACTIVITY | KNOLL AG (DE) | 1998-12-30 | — | — | EP | disclosed |
| EP-0705258-A1 | AZOLYL-CYCLIC AMINE DERIVATIVES WITH IMMUNOMODULATORY ACTIVITY | Knoll AG (DE) | 1996-04-10 | — | — | EP | disclosed |
| WO-1995000507-A1 | AZOLYL-CYCLIC AMINE DERIVATIVES WITH IMMUNOMODULATORY ACTIVITY | KNOLL AG (DE) | 1995-01-05 | — | — | WO | disclosed |