SCHEMBL854356

SCHEMBL854356

C=C[CH]c1ncccn1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL36385 0.75
SCHEMBL15054859 0.75 HDAC8 (0.35)
SCHEMBL6767656 0.74
SCHEMBL31107108 0.73
SCHEMBL2731913 0.71
SCHEMBL1389123 0.69
SCHEMBL8810777 0.69
SCHEMBL130185 0.69
SCHEMBL15870907 0.67 MEN1 (0.45)
SCHEMBL6158176 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 71 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115490668-B Pyrimidylimidazole compound, preparation method thereof and organic solderability preservative 深圳市贝加电子材料有限公司 2024-04-02 CN claimed
CN-115490668-A Pyrimidyl imidazole compound, preparation method thereof and organic weldable protective agent 深圳市贝加电子材料有限公司 2022-12-20 CN claimed
CN-102858743-A Spiro-condensed cyclohexane derivatives as HSL inhibitors useful for the treatment of diabetes HOFFMANN LA ROCHE 2013-01-02 CN claimed
CN-102421777-A Azacyclospiro derivatives as HSL inhibitors HOFFMANN LA ROCHE 2012-04-18 CN claimed
CN-100549011-C Novel imidazopyridine as cell cycle protein dependent kinase inhibitor SCHERING CORP (US) 2009-10-14 CN claimed
US-7071199-B1 Kinase inhibitors as therapeutic agents ABBOTT GMBH & CCO. KG (DE) 2006-07-04 US claimed
CN-1703414-A Novel imidazopyridines as cyclin dependent kinase inhibitors SCHERING CORP (US) 2005-11-30 CN claimed
CN-1227548-A Substituted p-trifluoromethylphenyluracils BAYER AG (DE) 1999-09-01 CN claimed
CN-1216538-A Substituted 2-aryl-1,2,4-triazine-3,5-di(thi) ones as herbicides BAYER AG (DE) 1999-05-12 CN claimed
CN-1192208-A Phenylpyridazinones BAYER AG (DE) 1998-09-02 CN claimed
EP-0544819-B1 INDOLE DERIVATIVES WHICH INHIBIT LEUKOTRIENE BIOSYNTHESIS ABBOTT LAB (US) 1995-12-06 EP claimed
EP-0544819-A4 INDOLE DERIVATIVES WHICH INHIBIT LEUKOTRIENE BIOSYNTHESIS 1993-10-20 EP claimed
EP-0544819-A1 INDOLE DERIVATIVES WHICH INHIBIT LEUKOTRIENE BIOSYNTHESIS. ABBOTT LAB (US) 1993-06-09 EP claimed
WO-1992003132-A1 INDOLE DERIVATIVES WHICH INHIBIT LEUKOTRIENE BIOSYNTHESIS ABBOTT LABORATORIES (US) 1992-03-05 WO claimed
EP-0349921-A2 Etheral n-terminal aminodiol amino acid derivatives as anti-hypertensive agents G.D. Searle & Co. (US) 1990-01-10 EP claimed
CN-115490668-B Pyrimidylimidazole compound, preparation method thereof and organic solderability preservative 深圳市贝加电子材料有限公司 2024-04-02 CN disclosed
CN-115490668-A Pyrimidyl imidazole compound, preparation method thereof and organic weldable protective agent 深圳市贝加电子材料有限公司 2022-12-20 CN disclosed
WO-1992003132-A1 INDOLE DERIVATIVES WHICH INHIBIT LEUKOTRIENE BIOSYNTHESIS ABBOTT LABORATORIES (US) 1992-03-05 WO disclosed
WO-1990000051-A1 ETHEREAL N-TERMINAL AMINODIOL AMINO ACID DERIVATIVES AS ANTI-HYPERTENSIVE AGENTS G.D. SEARLE & CO. (US) 1990-01-11 WO disclosed
EP-0349921-A2 Etheral n-terminal aminodiol amino acid derivatives as anti-hypertensive agents G.D. Searle & Co. (US) 1990-01-10 EP disclosed