Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 11/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TXN | P10599 | 1/20 | 0.39 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | TERT | O14746 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1665687 | 0.84 | — | — | |
| SCHEMBL25758352 | 0.80 | TAAR1 (0.46) | TAAR1ALOX15TXNTXNRD1HTR1A | |
| SCHEMBL10654795 | 0.79 | — | — | |
| SCHEMBL233107 | 0.79 | — | — | |
| SCHEMBL4775871 | 0.79 | ALOX15 (0.45) | TAAR1ALOX15HTR1ATERT | |
| SCHEMBL24387815 | 0.78 | SCN10A (0.46) | TAAR1ALOX15TXNTXNRD1HTR1A | |
| Bromide SCHEMBL31612168 | 0.78 | ALOX15 (0.44) | TAAR1ALOX15HTR1ATERT | |
| Hydrochloric Acid SCHEMBL28589773 | 0.78 | TAAR1 (0.47) | TAAR1ALOX15TXNTXNRD1HTR1A | |
| Hydrochloric Acid SCHEMBL28795928 | 0.78 | TAAR1 (0.47) | TAAR1ALOX15TXNTXNRD1HTR1A | |
| Hydrochloric Acid SCHEMBL26696102 | 0.78 | TAAR1 (0.47) | TAAR1ALOX15TXNTXNRD1HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0874842-A1 | MERCAPTOALKYLPEPTIDYL COMPOUNDS HAVING AN IMIDAZOLE SUBSTITUENT AND THEIR USE AS INHIBITORS OF MATRIX METALLOPROTEINASES (MMP) AND/OR TUMOUR NECROSIS FACTOR (TNF) | Darwin Discovery Limited (GB) | 1998-11-04 | — | — | EP | disclosed |
| WO-1997019075-A1 | MERCAPTOALKYLPEPTIDYL COMPOUNDS HAVING AN IMIDAZOLE SUBSTITUENT AND THEIR USE AS INHIBITORS OF MATRIX METALLOPROTEINASES (MMP) AND/OR TUMOUR NECROSIS FACTOR (TNF) | DARWIN DISCOVERY LIMITED (GB) | 1997-05-29 | — | — | WO | disclosed |