SCHEMBL8544231

SCHEMBL8544231

Cc1ccc(S(=O)(=O)Nc2cccc(OCCNc3ccncc3)c2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
F2 P00734 17/20 1.00
ALDH1A1 P00352 1/20 0.58
MAPT P10636 1/20 0.58
GAA P10253 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL8542002 0.90 F2 (0.98) F2GAA
SCHEMBL8543078 0.90 F2 (1.00) F2
Hydrochloric Acid SCHEMBL8543551 0.88 F2 (0.98) F2ALDH1A1
SCHEMBL8548899 0.88 F2 (0.82) F2GAA
SCHEMBL8544836 0.86 F2 (1.00) F2
SCHEMBL7337386 0.83 F2 (1.00) F2
SCHEMBL8550080 0.83 F2 (1.00) F2
SCHEMBL8546663 0.83 F2 (0.84) F2
SCHEMBL8547914 0.83 F2 (0.73) F2ALDH1A1
SCHEMBL8546386 0.83 F2 (0.73) F2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0687253-B1 4-AMINOPYRIDINES, PROCESS FOR PREPARING THE SAME AND MEDICAMENTS CONTAINING THE SAME BOEHRINGER MANNHEIM GMBH (DE) 1998-12-16 EP disclosed