Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 15/20 | 0.82 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.60 |
| ▸ | BRAF | P15056 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.47 |
| ▸ | AR | P10275 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7331309 | 0.92 | F2 (0.77) | F2EPHX2BRAFAR | |
| Hydrochloric Acid SCHEMBL8542002 | 0.89 | F2 (0.98) | F2GAA | |
| SCHEMBL8543078 | 0.89 | F2 (1.00) | F2 | |
| SCHEMBL8544231 | 0.88 | F2 (1.00) | F2GAA | |
| Hydrochloric Acid SCHEMBL8543551 | 0.87 | F2 (0.98) | F2 | |
| SCHEMBL8544836 | 0.85 | F2 (1.00) | F2 | |
| SCHEMBL7359983 | 0.82 | ROCK2 (0.62) | F2EPHX2GAA | |
| SCHEMBL7337386 | 0.82 | F2 (1.00) | F2 | |
| SCHEMBL8546386 | 0.82 | F2 (0.73) | F2EPHX2 | |
| SCHEMBL8547914 | 0.82 | F2 (0.73) | F2EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0687253-B1 | 4-AMINOPYRIDINES, PROCESS FOR PREPARING THE SAME AND MEDICAMENTS CONTAINING THE SAME | BOEHRINGER MANNHEIM GMBH (DE) | 1998-12-16 | — | — | EP | disclosed |