Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 10/20 | 0.61 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.61 |
| ▸ | PDE4D | Q08499 | 11/20 | 0.46 |
| ▸ | PDE4C | Q08493 | 6/20 | 0.45 |
| ▸ | TOP1 | P11387 | 1/20 | 0.44 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.42 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.41 |
| ▸ | MET | P08581 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7449137 | 0.85 | PDE4A (0.66) | PDE4APDE4BPDE4DPDE4CTOP1 | |
| Hydrochloric Acid SCHEMBL7438842 | 0.84 | PDE4A (0.65) | PDE4APDE4BPDE4DPDE4CTOP1 | |
| SCHEMBL7440005 | 0.81 | PDE4A (0.69) | PDE4APDE4BPDE4DPDE4CTOP1 | |
| Hydrochloric Acid SCHEMBL7440541 | 0.80 | PDE4A (0.67) | PDE4APDE4BPDE4DPDE4CTOP1 | |
| SCHEMBL7441893 | 0.78 | PDE4A (0.74) | PDE4APDE4BPDE4DPDE4CTOP1 | |
| SCHEMBL7450694 | 0.78 | PDE4A (0.74) | PDE4APDE4BPDE4DPDE4CTOP1 | |
| SCHEMBL3788376 | 0.78 | PELI1 (0.46) | PDE4BP2RX7IRAK4 | |
| SCHEMBL7437116 | 0.78 | PDE4A (0.70) | PDE4APDE4BPDE4DPDE4CTOP1 | |
| SCHEMBL7446433 | 0.77 | PDE4A (0.61) | PDE4APDE4BPDE4DPDE4CTOP1 | |
| SCHEMBL7441455 | 0.77 | PDE4A (0.66) | PDE4APDE4BPDE4DPDE4CTOP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0691966-B1 | QUINOLINES AS TYPE IV PHOSPHODIESTERASE INHIBITORS | SYNTEX INC (US) | 1998-09-09 | — | — | EP | disclosed |