Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 15/20 | 0.51 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8541916 | 0.82 | TBXAS1 (0.55) | TBXAS1KCNA5L3MBTL1 | |
| SCHEMBL8542287 | 0.82 | TBXAS1 (0.65) | TBXAS1PTGDR2 | |
| SCHEMBL8543330 | 0.81 | TBXAS1 (0.46) | TBXAS1ALDH1A1CYP1A2HPGDKCNA5 | |
| SCHEMBL8578689 | 0.80 | HPGD (0.44) | TBXAS1PTGDR2ALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL8304970 | 0.79 | TBXAS1 (0.69) | TBXAS1 | |
| SCHEMBL8543141 | 0.76 | TBXAS1 (0.46) | TBXAS1ALDH1A1KCNA5 | |
| SCHEMBL13774769 | 0.74 | KMT2A (0.56) | ALDH1A1CYP1A2CYP2C9HPGDKCNA5 | |
| SCHEMBL8543137 | 0.73 | TLR7 (0.42) | TBXAS1ALDH1A1KCNA5 | |
| SCHEMBL8539545 | 0.71 | TBXAS1 (0.67) | TBXAS1PTGDR2 | |
| SCHEMBL8544227 | 0.71 | TBXAS1 (0.46) | TBXAS1ALDH1A1CYP1A2CYP2C9HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0715627-B1 | INDOLE DERIVATIVES AS THROMBOXANE A2 ANTAGONISTS | PFIZER LTD (GB) | 1998-09-09 | — | — | EP | claimed |