Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13784551 | 0.85 | MAPT (0.60) | MAPTL3MBTL1ALDH1A1ALOX15POLB | |
| SCHEMBL5267824 | 0.85 | MAPT (0.60) | MAPTL3MBTL1ALDH1A1ALOX15POLB | |
| SCHEMBL272026 | 0.83 | MAPT (0.81) | MAPTL3MBTL1ALDH1A1ALOX15NPC1 | |
| SCHEMBL5267244 | 0.83 | MAPT (0.57) | MAPTL3MBTL1ALDH1A1ALOX15POLB | |
| SCHEMBL13444683 | 0.80 | MAPT (0.55) | MAPTL3MBTL1ALDH1A1ALOX15POLB | |
| SCHEMBL9168331 | 0.80 | MAPT (0.62) | MAPTL3MBTL1ALDH1A1ALOX15NPC1 | |
| SCHEMBL11649910 | 0.80 | MAPT (0.62) | MAPTL3MBTL1ALDH1A1ALOX15POLB | |
| SCHEMBL28122337 | 0.80 | MAPT (0.62) | MAPTL3MBTL1ALDH1A1ALOX15POLB | |
| SCHEMBL10771802 | 0.80 | MAPT (0.62) | MAPTL3MBTL1ALDH1A1ALOX15NPC1 | |
| SCHEMBL20299545 | 0.79 | MAPT (0.60) | MAPTL3MBTL1ALDH1A1ALOX15POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0842161-A1 | 4,5-DIARYL OXAZOLE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-05-20 | — | — | EP | disclosed |