Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.45 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10771802 | 1.00 | MAPT (0.62) | MAPTL3MBTL1ALOX15ALDH1A1NPC1 | |
| SCHEMBL272026 | 0.86 | MAPT (0.81) | MAPTL3MBTL1ALOX15ALDH1A1NPC1 | |
| SCHEMBL11649910 | 0.83 | MAPT (0.62) | MAPTL3MBTL1ALOX15ALDH1A1NPC1 | |
| SCHEMBL28122337 | 0.83 | MAPT (0.62) | MAPTL3MBTL1ALOX15ALDH1A1NPC1 | |
| SCHEMBL28425776 | 0.81 | MAPT (0.60) | MAPTL3MBTL1ALOX15ALDH1A1NPC1 | |
| SCHEMBL13784551 | 0.81 | MAPT (0.60) | MAPTL3MBTL1ALOX15ALDH1A1NPC1 | |
| SCHEMBL20299545 | 0.81 | MAPT (0.60) | MAPTL3MBTL1ALOX15ALDH1A1NPC1 | |
| SCHEMBL5267824 | 0.81 | MAPT (0.60) | MAPTL3MBTL1ALOX15ALDH1A1NPC1 | |
| SCHEMBL11613509 | 0.81 | MAPT (0.52) | MAPTL3MBTL1ALOX15ALDH1A1NPC1 | |
| SCHEMBL8544797 | 0.80 | MAPT (0.59) | MAPTL3MBTL1ALOX15ALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0382220-B1 | Method for preparing aminothiazolylacetic acid derivatives | MEIJI SEIKA KAISHA (JP) | 1995-06-28 | — | — | EP | disclosed |
| EP-0227953-B1 | NEW CEPHALOSPORIN DERIVATIVES AND ANTIBIOTICS CONTAINING THE SAME | MEIJI SEIKA KAISHA LTD. (JP) | 1993-02-03 | — | — | EP | disclosed |
| EP-0382220-A2 | Method for preparing aminothiazolylacetic acid derivatives | MEIJI SEIKA KAISHA LTD. (JP) | 1990-08-16 | — | — | EP | disclosed |
| US-4898858-A | Cephalosporin derivatives and antibiotics containing the same | MEIJI SEIKA KAISHA LTD. (JP) | 1990-02-06 | — | — | US | disclosed |
| EP-0227953-A2 | New cephalosporin derivatives and antibiotics containing the same | MEIJI SEIKA KAISHA LTD. (JP) | 1987-07-08 | — | — | EP | disclosed |